How much is the bus ticket from Orlando to Panama City?

The cheapest bus tickets from Orlando to Panama City start from $60. The average price for this route is around $106. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Orlando to Panama City?

The average bus trip duration from Orlando to Panama City is 9h 20m, covering a distance of 289 miles (467 km). The quickest bus can get you there in 8h 55m and is operated by FlixBus .

Which bus companies service the Orlando to Panama City route?

Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Orlando to Panama City?

The earliest bus departs from Orlando to Panama City at 5:40am. And the latest bus departs at 1:50pm.

What are the CO₂ emissions for the bus trip from Orlando to Panama City?

A bus trip from Orlando to Panama City generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Orlando to Panama City?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87412 reviews.

Which bus company has the best Wi-Fi from Orlando to Panama City?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Orlando to Panama City?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Orlando to Panama City?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Orlando to Panama City from $56 | Refundable Tickets

Next bus departures

Next departures for Orlando to Panama City on December 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	1:05pm	The Florida Mall	9h 30m	9:35pm	Panama City Beach Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	1:50pm	Orlando Bus Station	8h 45m	9:35pm	Panama City Beach Station	Fastest

Next departures for Orlando to Panama City on December 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	5:40am	Orlando Bus Station	9h 20m	2:00pm	Panama City Beach Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	1:50pm	Orlando Bus Station	8h 45m	9:35pm	Panama City Beach Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	1:05pm	The Florida Mall	9h 30m	9:35pm	Panama City Beach Station	No tags

Next departures for Orlando to Panama City on December 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	1:50pm	Orlando Bus Station	8h 45m	9:35pm	Panama City Beach Station	CheapestFastest
	Bus	5:40am	Orlando Bus Station	9h 20m	2:00pm	Panama City Beach Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	1:05pm	The Florida Mall	9h 30m	9:35pm	Panama City Beach Station	No tags

Next departures for Orlando to Panama City on December 19
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	1:50pm	Orlando Bus Station	8h 45m	9:35pm	Panama City Beach Station	CheapestFastest
	Bus	5:40am	Orlando Bus Station	9h 20m	2:00pm	Panama City Beach Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	1:05pm	The Florida Mall	9h 30m	9:35pm	Panama City Beach Station	No tags

Last refresh of the prices: Last Thursday at 2:10 AM EST.

Get from Orlando to Panama City

This route is served by bus only

The journey takes about 9 hours 20 minutes and with fares starting at just $60, it presents an excellent value for a comfortable ride.

3bus per day

9h 20mAverage Duration

289 milesDistance

12kgCO₂ emissions

Where are the popular stops in Orlando and Panama City?

Stops in Orlando

A
Orlando Bus Station
555 N John Young Pkwy, Orlando, FL 32805
Visit page
B
Orlando RedCoach Station
RedCoach Station, 1777 McCoy Road, Orlando, FL 32809
Visit page
C
Jet Set Express Terminal
Jet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
Visit page
D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830
E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA
F
Seaworld Hotels
10100 International Drive , Orlando, 32821

Stops in Panama City

A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401

Compare bus companies

Greyhound

3.5/587,432 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound Orlando Panama City recent customer reviews

The journey was very pleasant, thanks to the team of experienced, helpful and caring workers. I did not like the long layover.

Sharon D.

December 24, 2023

My major issue was that I could not connect to the WiFi. My final arrangements for my pickup wasn't made. I was depending on the bus WiFi for that. As the bus was delayed, the layover at Tallahassee was shortened to half hour. By the time I got food I had little time to communicate with my pickup. Food was horrible. I decided final contract could still be made using the WiFi at the Panama City Terminal. But they. Had no WiFi.

Quasheba C.

May 25, 2019

The staff is good at some point but at others they need to improve. Also there needs to be some earlier buses to destinations like Panama City

Jefroy A.

May 17, 2019

FlixBus

3.5/511,621 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Orlando to Panama City, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Orlando to Panama City?
The cheapest bus tickets from Orlando to Panama City start from $60. The average price for this route is around $106. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Orlando to Panama City?
The average bus trip duration from Orlando to Panama City is 9h 20m, covering a distance of 289 miles (467 km). The quickest bus can get you there in 8h 55m and is operated by FlixBus.
Which bus companies service the Orlando to Panama City route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Orlando to Panama City?
The earliest bus departs from Orlando to Panama City at 5:40am. And the latest bus departs at 1:50pm.
What are the CO₂ emissions for the bus trip from Orlando to Panama City?
A bus trip from Orlando to Panama City generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Orlando to Panama City?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Orlando to Panama City?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Orlando to Panama City?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Orlando to Panama City?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/13

$106

12/14

$103

Today

$88

12/16

$73

12/17

$74

12/18

$81

12/19

$103

12/20

$93

The cheapest trip from Orlando to Panama City, US was searched and found on Dec 16, 2025 with a price of $73

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Panama City, US, as early as possible.

You can expect to pay from $73 to $106 for a bus ticket from Orlando to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $73 which is on 2025-12-16.