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One passenger / one way
- This trip is recommended because it is: Cheapest + FastestDeparture time: June 16 atDeparture city: LouisvilleDeparture location: Louisville, KYArrival time: June 17 atDestination city: WythevilleDestination location: Wytheville Bus StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: June 16 atDeparture city: LouisvilleDeparture location: Louisville, KYArrival time: June 17 atDestination city: WythevilleDestination location: Wytheville Bus StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
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Bus Louisville to Wytheville: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Louisville to Wytheville Bus
Busbud helps you find a bus from Louisville to Wytheville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Louisville to Wytheville.
Whether it is cheap bus tickets or more luxurious buses going to Wytheville from Louisville, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Louisville - Wytheville
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Louisville to Wytheville was searched and found on Jun 16, 2025 with a price of $132To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Wytheville, as early as possible.
You can expect to pay from $132 to $150 for a bus ticket from Louisville to Wytheville based on the last 2 days. You can expect to find the cheapest price for the trip at $132 which is on 2025-06-16.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Louisville and Wytheville!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Louisville to Wytheville.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Louisville to Wytheville.
Make a music playlist for your bus ride from Louisville to Wytheville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top traveled bus routes
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