Bus Tickets from Jacksonville, FL to San Diego, CA, US

Next departures

Next departures for Jacksonville to San Diego on September 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Jacksonville Bus Station
UCSD Health La Jolla StationCheapest
Greyhound Lines, Inc.
Jacksonville Bus Station
Greyhound Bus StopFastest
FlixBus + Greyhound Lines, Inc.
Jacksonville Bus Station
San Diego (Old Town-FlixBus)No tags
Greyhound Lines, Inc.
Jacksonville Bus Station
Greyhound Bus StopNo tags
FlixBus + Greyhound Lines, Inc.
Jacksonville Bus Station
San Diego (Old Town-FlixBus)No tags

Accepted payments

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Compare 2 ways to go from Jacksonville to San Diego.

Bus
Average Price$222 - $609Average Duration2d 15h
84kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$577 - $706Average Duration3d 22h
305kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Jacksonville to San Diego

Among the sustainable travel choices, the bus stands out as the good way to reach San Diego. The journey takes about 2 days, 15 hours 5 minutes and with fares starting at just $222, it presents an excellent value for a comfortable ride.

9bus per day
2d 15hAverage Duration
$222Cheapest ticket
84kgCO₂ emissions

Bus Jacksonville, FL to San Diego, CA, US: Trip Overview

Average ticket price$348
Average bus trip duration2d 15h
Number of daily buses9
Earliest bus departure8:05am
Distance2085 miles (3362 km)
Latest bus departure9:25pm

Jacksonville to San Diego Bus

Busbud helps you find a bus from Jacksonville to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Jacksonville to San Diego from the most reliable bus companies operating this trip.

Discover how much the bus trip from Jacksonville to San Diego will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Jacksonville, FL - San Diego, CA, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/01
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09/02
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Today
$370
09/04
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09/05
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09/06
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busbud logoThe cheapest trip from Jacksonville, FL to San Diego, CA, US was searched and found on Sep 3, 2025 with a price of $370

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to San Diego, CA, US, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Jacksonville and San Diego!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Jacksonville to San Diego, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Jacksonville to San Diego will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Jacksonville to San Diego while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Jacksonville, FL to San Diego, CA, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jacksonville, FL by bus?

Bus from San Diego, CA, US to Jacksonville, FL

You can also go to San Diego, CA, US by train

Train from Jacksonville, FL to San Diego, CA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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