How much is the bus ticket from Greenville to Columbus?

The cheapest bus tickets from Greenville to Columbus start from $104. The average price for this route is around $169. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Greenville to Columbus?

The average bus trip duration from Greenville to Columbus is 17h, covering a distance of 356 miles (574 km). The quickest bus can get you there in 17h and is operated by Greyhound .

Which bus companies service the Greenville to Columbus route?

Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Greenville to Columbus?

The earliest bus departs from Greenville to Columbus at 2:45pm. And the latest bus departs at 10:00pm.

What are the CO₂ emissions for the bus trip from Greenville to Columbus?

A bus trip from Greenville to Columbus generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Greenville to Columbus?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87463 reviews.

Which bus company has the best Wi-Fi from Greenville to Columbus?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Greenville to Columbus?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Greenville to Columbus?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Greenville to Columbus from $105 | Refundable Tickets

Next bus departures

Next departures for Greenville to Columbus on January 11
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	2:45pm	1116 Woodruff Rd	17h	7:45am	Columbus (E Mound St)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	14h 55m	12:55pm	Columbus (E Mound St)	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	7:45pm	1116 Woodruff Rd	1d	7:50pm	100 E Rich St	No tags

Next departures for Greenville to Columbus on January 12
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	14h 55m	12:55pm	Columbus (E Mound St)	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	7:45pm	1116 Woodruff Rd	1d	7:50pm	100 E Rich St	No tags
	Bus	2:45pm	1116 Woodruff Rd	17h	7:45am	Columbus (E Mound St)	No tags

Last refresh of the prices: Last Thursday at 12:10 AM EST.

Get from Greenville to Columbus

This route is served by bus only

The journey takes about 17 hours and with fares starting at just $104, it presents an excellent value for a comfortable ride.

3bus per day

17hAverage Duration

356 milesDistance

14kgCO₂ emissions

Where are the popular stops in Greenville and Columbus?

Stops in Greenville

A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611
Map
B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Map

Stops in Columbus

A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA
Map

Compare bus companies

Greyhound

3.5/587,492 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,996 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Greenville, SC to Columbus, OH by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Greenville to Columbus?
The cheapest bus tickets from Greenville to Columbus start from $104. The average price for this route is around $169. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Columbus?
The average bus trip duration from Greenville to Columbus is 17h, covering a distance of 356 miles (574 km). The quickest bus can get you there in 17h and is operated by Greyhound.
Which bus companies service the Greenville to Columbus route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Greenville to Columbus?
The earliest bus departs from Greenville to Columbus at 2:45pm. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Columbus?
A bus trip from Greenville to Columbus generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Greenville to Columbus?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Greenville to Columbus?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Greenville to Columbus?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Columbus?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/08

$170

01/09

$171

Today

No data

01/11

$105

01/12

$129

01/13

No data

01/14

No data

01/15

No data

The cheapest trip from Greenville, SC to Columbus, OH was searched and found on Jan 11, 2026 with a price of $105

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Columbus, OH, as early as possible.

You can expect to pay from $105 to $171 for a bus ticket from Greenville, SC to Columbus, OH based on the last 2 days. You can expect to find the cheapest price for the trip at $105 which is on 2026-01-11.