Bus Tickets from Gainesville, FL to Columbia, SC

Find affordable bus tickets from Gainesville, FL to Columbia, SC with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Frequently asked questions for your trip Gainesville, FL - Columbia, SC

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/11
No data
07/12
No data
Today
No data
07/14
No data
07/15
No data
07/16
No data
07/17
No data
07/18
$65
busbud logoThe cheapest trip from Gainesville to Columbia was searched and found on Jul 18, 2025 with a price of $65

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville to Columbia, as early as possible.

You can expect to pay from $65 to $324 for a bus ticket from Gainesville to Columbia based on the last 2 days. You can expect to find the cheapest price for the trip at $65 which is on 2025-07-18.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Gainesville and Columbia!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Gainesville to Columbia, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Gainesville to Columbia.

Make a music playlist for your bus ride from Gainesville to Columbia, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Gainesville by bus?

Bus from Gainesville to Columbia

You can also go to Columbia, SC by train

Train from Gainesville, FL to Columbia, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Gainesville

Buses Leaving from Gainesville

Buses Going to Gainesville

Popular Buses Connecting Columbia

Buses Leaving from Columbia

Buses Going to Columbia