Bus Tickets from Gainesville, FL to Charlotte, NC

Find affordable bus tickets from Gainesville, FL to Charlotte, NC with flexible options. Book your trip now

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TodayJul 27
from $106
TomorrowJul 28
from $95
TueJul 29
from $74
WedJul 30
ThuJul 31
FriAug 1
SatAug 2
from $100
SunAug 3

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 28 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: July 28 at
    Destination city: Charlotte
    Destination location: Charlotte (Freedom Dr)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 28 at
    Departure city: Gainesville
    Departure location: Rosa Parks Station
    Arrival time: July 28 at
    Destination city: Charlotte
    Destination location: Charlotte (Freedom Dr)
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: July 28 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: July 28 at
    Destination city: Charlotte
    Destination location: Charlotte Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 28 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: July 29 at
    Destination city: Charlotte
    Destination location: Charlotte Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: July 28 at
    Departure city: Gainesville
    Departure location: Rosa Parks Station
    Arrival time: July 28 at
    Destination city: Charlotte
    Destination location: Charlotte Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Bus Gainesville, FL to Charlotte, NC: Trip Overview

Average ticket price$106
Average bus trip duration12h 40m
Number of daily buses10
Earliest bus departure1:10am
Distance395 miles (637 km)
Latest bus departure8:00pm

Gainesville to Charlotte Bus

Busbud helps you find a bus from Gainesville to Charlotte. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Gainesville to Charlotte.

From cheap bus tickets to more luxurious buses traveling from Gainesville to Charlotte, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Gainesville, FL - Charlotte, NC

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/25
$95
07/26
$105
Today
$98
07/28
$87
07/29
$66
07/30
No data
07/31
No data
08/01
No data
busbud logoThe cheapest trip from Gainesville, FL to Charlotte, NC was searched and found on Jul 29, 2025 with a price of $66

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Charlotte, NC, as early as possible.

You can expect to pay from $66 to $789 for a bus ticket from Gainesville, FL to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at $66 which is on 2025-07-29.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Gainesville and Charlotte!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Gainesville to Charlotte.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Gainesville to Charlotte that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Gainesville to Charlotte while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Gainesville, FL by bus?

Bus from Gainesville, FL to Charlotte, NC

You can also go to Charlotte, NC by train

Train from Gainesville, FL to Charlotte, NC

Why choose Busbud?

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Popular bus departures from Gainesville

Popular bus departures to Gainesville

Continue your journey from Charlotte