Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Durham Greyhound Bus Station | 1116 Woodruff Rd | No tags | ||||
 | Bus | BP Gas Station | 1111 Woodruff Road | No tags | ||||
 | Bus | Durham Greyhound Bus Station | 1116 Woodruff Rd | No tags | ||||
| Bus | Durham Greyhound Bus Station | 1116 Woodruff Rd | No tags | ||||
| Bus | Durham Greyhound Bus Station | 1116 Woodruff Rd | No tags |
Compare 2 ways to go from Durham to Greenville
Among the sustainable travel choices, the Bus stands out as the good way to reach Greenville. The journey takes about 4 hours 45 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.
Where are the popular stops in Durham and Greenville?
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
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Frequently asked questions about traveling from Durham, NC, US to Greenville, SC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Durham to Greenville?
The cheapest bus tickets from Durham to Greenville start from $44. The average price for this route is around $62. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Durham to Greenville?
The average bus trip duration from Durham to Greenville is 4h 45m, covering a distance of 217 miles (349 km). The quickest bus can get you there in 4h 30m and is operated by Tornado Bus.
Which bus companies service the Durham to Greenville route?
Several major bus companies operate on this route with 8 buses available per day, including services from FlixBus, Tornado Bus, Wanda Coach, Greyhound.
What is the earliest and latest departure time for the bus from Durham to Greenville?
The earliest bus departs from Durham to Greenville at 1:30am. And the latest bus departs at 2:50pm.
What are the CO₂ emissions for the bus trip from Durham to Greenville?
A bus trip from Durham to Greenville generates an estimated 9 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Durham to Greenville?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11828 reviews.
Which bus company has the best Wi-Fi from Durham to Greenville?
Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 4.1.
Which bus company has the most timely service from Durham to Greenville?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Durham to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Greenville, SC was searched and found on Jan 10, 2026 with a price of $41To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Greenville, SC, as early as possible.
You can expect to pay from $41 to $145 for a bus ticket from Durham, NC, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $44 which is on 2026-01-12.
What's the cheapest way to go from Durham, NC, US to Greenville, SC?
The Bus is the cheapest travel choice for this destination
