Bus Tickets from Durham (NC), US to Greenville (SC)

Find affordable bus tickets from Durham (NC), US to Greenville (SC) with flexible options. Book your trip now

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FriJun 6
SatJun 7
from US$48
SunJun 8
MonJun 9
TueJun 10
from US$40
WedJun 11
ThuJun 12
FriJun 13

Cheap buses leaving Saturday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 7 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: June 7 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 7 at
    Departure city: Durham
    Departure location: Durham
    Arrival time: June 7 at
    Destination city: Greenville
    Destination location: Greenville, (SC - Taqueria Guadalajara #3)
    Operated by: Tornado BusTornado Bus
    Vehicle: BusDuration:
  • Departure time: June 7 at
    Departure city: Durham
    Departure location: BP Gas Station
    Arrival time: June 7 at
    Destination city: Greenville
    Destination location: 1111 Woodruff Road
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: June 7 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: June 7 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 7 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: June 7 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Saturday at 2:54 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Durham to Greenville

Bus
Average PriceUS$42 - US$137Average Duration4h 45m
8kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$67 - US$104Average Duration11h 20m
31kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Durham to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 4 hours 45 minutes, and with fares starting at just US$42, it presents an excellent value for a comfortable ride.

8bus per day
4h 45mAverage Duration
US$42Cheapest ticket
8kgCO₂ emissions

Bus Durham to Greenville: Trip Overview

Average Ticket PriceUS$50
Average Bus Trip Duration4h 45m
Number of daily buses8
Earliest bus departure1:30am
Distance334 km
Latest bus departure2:50pm

Durham to Greenville Bus

Busbud helps you find a bus from Durham to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Greenville.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from Durham, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Durham (NC), US - Greenville (SC)

  1. How long is the bus trip from Durham to Greenville?

    The typical travel time from Durham to Greenville by bus is around 4h 45m. The fastest bus on this trip will get to Greenville in 4h 30m

  2. How far is Durham from Greenville?

    The distance between Durham and Greenville is around 342 km (212 miles).

  3. What are the departure and arrival locations for buses traveling from Durham to Greenville?

    Buses traveling this route start their trip at Durham Greyhound Bus Station, in Durham, and end it at Guadalajara Supermarket Bus Stop, in Greenville.

  4. What is the cheapest way to go from Durham to Greenville?

    The least expensive option to go from Durham to Greenville would be going by bus. The ticket price for this bus starts at US$42, making this your best choice for this trip.

  5. How much does it cost to take the bus from Durham to Greenville?

    Taking the bus from Durham to Greenville costs on average US$50.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-02
US$36
06-03
US$35
Today
US$34
06-05
US$37
06-06
No data
06-07
US$40
06-08
No data
06-09
US$36
busbud logoThe cheapest trip from Durham to Greenville was searched and found on Jun 4, 2025 with a price of US$34

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham to Greenville, as early as possible.

You can expect to pay from US$34 to US$130 for a bus ticket from Durham to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at US$36 which is on 2025-06-09.

Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Greenville!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Durham to Greenville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Greenville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Greenville.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Durham to Greenville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Durham by bus?

Bus from Durham to Greenville

You can also go to Greenville by train

Train from Durham to Greenville

Why choose Busbud?

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