Bus Tickets from Durham, NC, US to Greenville, SC

TodayAug 1
TomorrowAug 2
SunAug 3
from US$49
MonAug 4
from US$44
TueAug 5
from US$42
WedAug 6
from US$42
ThuAug 7
from US$44
FriAug 8

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 3 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: August 3 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 3 at
    Departure city: Durham
    Departure location: Durham
    Arrival time: August 3 at
    Destination city: Greenville
    Destination location: Greenville, (SC - Taqueria Guadalajara #3)
    Operated by: Tornado BusTornado Bus
    Vehicle: BusDuration:
  • Departure time: August 3 at
    Departure city: Durham
    Departure location: BP Gas Station
    Arrival time: August 3 at
    Destination city: Greenville
    Destination location: 1111 Woodruff Road
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: August 3 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: August 3 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 3 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: August 3 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 5:25 PM EDT.

Prices and availability are subject to change.

Accepted payments

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  • American Express
  • China Union Pay
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  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Durham to Greenville

Bus
Average PriceUS$37 - US$164Average Duration4h 45m
8kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$67 - US$127Average Duration10h 23m
31kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Durham to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 4 hours 45 minutes, and with fares starting at just US$37, it presents an excellent value for a comfortable ride.

8bus per day
4h 45mAverage Duration
US$37Cheapest ticket
8kgCO₂ emissions

Bus Durham, NC, US to Greenville, SC: Trip Overview

Average Ticket PriceUS$52
Average Bus Trip Duration4h 45m
Number of daily buses8
Earliest bus departure1:30am
Distance334 km
Latest bus departure2:50pm

Durham to Greenville Bus

Busbud helps you find a bus from Durham to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Greenville.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from Durham, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Durham, NC, US - Greenville, SC

  1. How far is Durham from Greenville?

    The distance between Durham and Greenville is around 342 km (212 miles).

  2. What are the departure and arrival locations for buses traveling from Durham to Greenville?

    Buses traveling this route start their trip at Durham Greyhound Bus Station, in Durham, and end it at Guadalajara Supermarket Bus Stop, in Greenville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-30
US$35
07-31
US$40
Today
US$42
08-02
US$36
08-03
US$41
08-04
US$36
08-05
US$34
08-06
US$34
busbud logoThe cheapest trip from Durham, NC, US to Greenville, SC was searched and found on Aug 5, 2025 with a price of US$34

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Greenville, SC, as early as possible.

You can expect to pay from US$34 to US$155 for a bus ticket from Durham, NC, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$34 which is on 2025-08-05.

Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Greenville!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Durham to Greenville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Greenville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Greenville.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Durham, NC, US to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Durham, NC, US by bus?

Bus from Durham, NC, US to Greenville, SC

You can also go to Greenville, SC by train

Train from Durham, NC, US to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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Popular Buses Connecting Durham

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