How far is Durham from Chicago?

The distance separating Durham and Chicago is 620 miles (999 km).

What are the departure and arrival stations when taking the bus from Durham to Chicago?

Most of the buses traveling from Durham to Chicago leave from Durham Greyhound Bus Station and arrive at Downtown Greyhound Station. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Chicago?

Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Lincoln Park Conservatory, Navy Pier, Brookfield Zoo, Auditorium Building and Theatre and Museum of Science and Industry.

Bus Durham to Chicago from $73 | Refundable Tickets

Next departures

Next departures for Durham to Chicago on September 14
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	1:20am	Durham Greyhound Bus Station	23h 20m	11:40pm	Downtown Greyhound Station	Cheapest
	2:30am	Durham Greyhound Bus Station	22h 20m	11:50pm	Chicago 95Th & Dan Ryan	Fastest
	2:30am	Durham Greyhound Bus Station	22h 40m	12:10am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	8:35am	Durham Greyhound Bus Station	1d	8:15am	Downtown Greyhound Station	No tags
	9:10am	Durham Greyhound Bus Station	1d 6h	2:10pm	537-517 W. Jackson Blvd	No tags

Next departures for Durham to Chicago on September 15
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	2:30am	Durham Greyhound Bus Station	22h 40m	12:10am	Downtown Greyhound Station	Cheapest
	2:30am	Durham Greyhound Bus Station	22h 20m	11:50pm	Chicago 95Th & Dan Ryan	Fastest
FlixBus + Greyhound Lines, Inc.	1:20am	Durham Greyhound Bus Station	23h 20m	11:40pm	Downtown Greyhound Station	No tags
	3:55am	Durham Greyhound Bus Station	1d 2h	5:45am	Downtown Greyhound Station	No tags
	9:10am	Durham Greyhound Bus Station	1d 6h	2:10pm	537-517 W. Jackson Blvd	No tags

Next departures for Durham to Chicago on September 16
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	3:55am	Durham Greyhound Bus Station	1d 2h	5:45am	Downtown Greyhound Station	Cheapest
	2:30am	Durham Greyhound Bus Station	22h 20m	11:50pm	Chicago 95Th & Dan Ryan	Fastest
FlixBus + Greyhound Lines, Inc.	1:20am	Durham Greyhound Bus Station	23h 20m	11:40pm	Downtown Greyhound Station	No tags
	2:30am	Durham Greyhound Bus Station	22h 40m	12:10am	Downtown Greyhound Station	No tags
	9:10am	Durham Greyhound Bus Station	1d 6h	2:10pm	537-517 W. Jackson Blvd	No tags

Next departures for Durham to Chicago on September 17
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	3:55am	Durham Greyhound Bus Station	1d 2h	5:45am	Downtown Greyhound Station	Cheapest
	2:30am	Durham Greyhound Bus Station	22h 20m	11:50pm	Chicago 95Th & Dan Ryan	Fastest
FlixBus + Greyhound Lines, Inc.	1:20am	Durham Greyhound Bus Station	23h 20m	11:40pm	Downtown Greyhound Station	No tags
	2:30am	Durham Greyhound Bus Station	22h 40m	12:10am	Downtown Greyhound Station	No tags
	2:20pm	Durham Greyhound Bus Station	1d 1h	3:15pm	Downtown Greyhound Station	No tags

Next departures for Durham to Chicago on September 18
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	2:40am	Durham Greyhound Bus Station	1d 4h	6:10am	Downtown Greyhound Station	Cheapest
FlixBus + Greyhound Lines, Inc.	1:20am	Durham Greyhound Bus Station	23h 20m	11:40pm	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	8:35am	Durham Greyhound Bus Station	1d	8:15am	Downtown Greyhound Station	No tags
	2:20pm	Durham Greyhound Bus Station	1d 1h	3:15pm	Downtown Greyhound Station	No tags
	3:55am	Durham Greyhound Bus Station	1d 2h	5:20am	Chicago 95Th & Dan Ryan	No tags

Compare 2 ways to go from Durham to Chicago.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$76 - $271	Average Duration1d 2h	CO₂ emissions 25kg CO₂e5 out of 5 stars	CheapestFastestMost eco-friendly
Train	Average Price$190 - $357	Average Duration1d 15h	CO₂ emissions 91kg CO₂e1 out of 5 stars

Busbud recommends taking the bus from Durham to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 2 hours 15 minutes and with fares starting at just $76, it presents an excellent value for a comfortable ride.

17bus per day

1d 2hAverage Duration

$76Cheapest ticket

25kgCO₂ emissions

Bus Durham, NC, US to Chicago: Trip Overview

Average ticket price$151

Average bus trip duration1d 2h

Number of daily buses17

Earliest bus departure1:10am

Distance619 miles (998 km)

Latest bus departure10:05pm

Compare bus companies

FlixBus

3.5/510,497 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,249 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Senda Diamante

Durham to Chicago Bus

With Busbud, comparing and booking tickets for a bus from Durham to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Chicago.

From cheap bus tickets to more luxurious buses traveling from Durham to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Where are the popular stops in Durham and Chicago?

Stops in Durham

A - Durham Greyhound Bus Station

B - Compare Foods Durham

C - Durham Compare Foods Durham

D - Durham, NC

Stops in Chicago

A - Downtown Greyhound Station

B - Chicago O'Hare International Airport

C - Polk St & Canal St

D - Tornado Bus S Kedzie Ave

E - Cumberland CTA

F - Turimex California Ave

Frequently asked questions for your trip Durham, NC, US - Chicago

How far is Durham from Chicago?
What are the departure and arrival stations when taking the bus from Durham to Chicago?
What are the best sights and things to do in Chicago?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09/11

$87

09/12

$90

Today

No data

09/14

$97

09/15

$84

09/16

$78

09/17

$73

09/18

$109

The cheapest trip from Durham, NC, US to Chicago was searched and found on Sep 17, 2025 with a price of $73

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Chicago, as early as possible.

You can expect to pay from $73 to $172 for a bus ticket from Durham, NC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $73 which is on 2025-09-17.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Durham to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Durham to Chicago.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Durham to Chicago that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Durham to Chicago while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Durham, NC, US to Chicago?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time1d 2h	Avg Price$151	Daily Departures17
Vehicle TypeTrain	Travel Time1d 15h	Avg Price$276	Daily Departures1

Will you be returning to Durham, NC, US by bus?

Bus from Chicago to Durham, NC, US

You can also go to Chicago by train

Train from Durham, NC, US to Chicago

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Durham, NC, US to Chicago

Next departures

Compare 2 ways to go from Durham to Chicago.

Bus Durham, NC, US to Chicago: Trip Overview

Compare bus companies

Durham to Chicago Bus

Where are the popular stops in Durham and Chicago?

Frequently asked questions for your trip Durham, NC, US - Chicago

How far is Durham from Chicago?

What are the departure and arrival stations when taking the bus from Durham to Chicago?

What are the best sights and things to do in Chicago?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Durham, NC, US to Chicago?

Will you be returning to Durham, NC, US by bus?

You can also go to Chicago by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Durham

Buses Leaving from Durham

Buses Going to Durham

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago

Popular routes in this country

Popular airport transfers