Cheap buses leaving Monday
One passenger / one way
- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: FastestDeparture time: June 16 atDeparture city: DurhamDeparture location: Durham Greyhound Bus StationArrival time: June 16 atDestination city: ChicagoDestination location: Chicago 95Th & Dan RyanOperated by: FlixBus
Vehicle: BusDuration: - Departure time: June 16 atDeparture city: DurhamDeparture location: Durham Greyhound Bus StationArrival time: June 17 atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: FlixBusVehicle: BusDuration:
- Departure time: June 16 atDeparture city: DurhamDeparture location: Durham Greyhound Bus StationArrival time: June 17 atDestination city: ChicagoDestination location: 537-517 W. Jackson BlvdOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Last refresh of the prices: Last Sunday at 10:12 PM EDT.
Prices and availability are subject to change.
Accepted payments
Compare 2 ways to go from Durham to Chicago
Busbud recommends taking the bus from Durham to ChicagoAmong the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 2 hours 30 minutes, and with fares starting at just US$105, it presents an excellent value for a comfortable ride.
Bus Durham to Chicago: Trip Overview
Compare bus companies
Durham to Chicago Bus
With Busbud, comparing and booking tickets for a bus from Durham to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Chicago.
From cheap bus tickets to more luxurious buses travelling from Durham to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Durham and Chicago?
Frequently asked questions on the trip Durham (NC), US - Chicago
How long is the bus trip from Durham to Chicago?
The trip from Durham to Chicago will take on average 1d 2h. The fastest bus on this trip will get to Chicago in 22h 25m
How far is Durham from Chicago?
The distance between Durham and Chicago is around 999 km (620 miles).
What are the departure and arrival locations for buses traveling from Durham to Chicago?
Buses traveling this route start their trip at Durham Greyhound Bus Station, in Durham, and end it at Downtown Greyhound Station, in Chicago.
What is the cheapest way to go from Durham to Chicago?
If you're on a budget, consider traveling by bus to Chicago from Durham; it tends to be more affordable. The ticket price for this bus starts at US$105, making this your best choice for this trip.
How much does it cost to take the bus from Durham to Chicago?
Taking the bus from Durham to Chicago costs on average US$182.
Can I take an overnight bus from Durham to Chicago?
Yes! Catch buses leaving from Durham until 9:55pm and reaching Chicago on the following day.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham to Chicago was searched and found on Jun 19, 2025 with a price of US$97To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham to Chicago, as early as possible.
You can expect to pay from US$97 to US$265 for a bus ticket from Durham to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$97 which is on 2025-06-19.
Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Durham to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Durham to Chicago.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Durham to Chicago that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Durham to Chicago while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from Durham to Chicago?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.