Bus Tickets from Chicago to Harrisburg

Next departures

Next departures for Chicago to Harrisburg on September 17
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Downtown Greyhound Station
Harrisburg Bus StationCheapest
FlixBus
Chicago 95Th & Dan Ryan
HarrisburgFastest
Greyhound Lines, Inc.
Downtown Greyhound Station
Harrisburg Bus StationNo tags
FlixBus + Greyhound Lines, Inc.
Downtown Greyhound Station
Harrisburg Bus StationNo tags
FlixBus
Downtown Greyhound Station
HarrisburgNo tags

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Chicago to Harrisburg.

Bus
Average Price$61 - $230Average Duration18h 30m
23kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$102 - $389Average Duration17h 15m
84kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Chicago to Harrisburg

Among the sustainable travel choices, the bus stands out as the good way to reach Harrisburg. The journey takes about 18 hours 30 minutes and with fares starting at just $61, it presents an excellent value for a comfortable ride.

15bus per day
18h 30mAverage Duration
$61Cheapest ticket
23kgCO₂ emissions

Bus Chicago to Harrisburg: Trip Overview

Average ticket price$91
Average bus trip duration18h 30m
Number of daily buses15
Earliest bus departure5:45am
Distance568 miles (916 km)
Latest bus departure11:50pm

Chicago to Harrisburg Bus

With Busbud, comparing and booking tickets for a bus from Chicago to Harrisburg is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Chicago to Harrisburg.

From cheap bus tickets to more luxurious buses traveling from Chicago to Harrisburg, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Chicago - Harrisburg

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/14
$117
09/15
$110
Today
$75
09/17
$53
09/18
$57
09/19
$69
09/20
$66
09/21
$67
busbud logoThe cheapest trip from Chicago to Harrisburg was searched and found on Sep 17, 2025 with a price of $53

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Harrisburg, as early as possible.

You can expect to pay from $53 to $147 for a bus ticket from Chicago to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $53 which is on 2025-09-17.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Chicago to Harrisburg.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Chicago to Harrisburg.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to Harrisburg that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Chicago to Harrisburg, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Chicago to Harrisburg?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Chicago by bus?

Bus from Harrisburg to Chicago

You can also go to Harrisburg by train

Train from Chicago to Harrisburg

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

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