What is the travel distance from Chicago to Durham?

The distance between the two cities is 620 miles (999 km).

What are the departure and arrival stations when taking the bus from Chicago to Durham?

The majority of buses traveling from Chicago to Durham start their journey at Downtown Greyhound Station and wind up at Durham Greyhound Bus Station. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Durham?

Once in Durham, you can start exploring the city and discover its surroundings. The top sights and things to do are HMS Trincomalee Trust, Auckland Castle, Crook Hall, Hall Hill Farm and Durham Castle.

Bus Chicago to Durham from $75 | Refundable Tickets

Next departures

Next departures for Chicago to Durham on September 17
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	11:59pm	Downtown Greyhound Station	1d	1:15am	Durham Greyhound Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	6:55am	Downtown Greyhound Station	1d	8:30am	Durham Greyhound Bus Station	No tags
	2:45pm	Downtown Greyhound Station	1d	4:15pm	Durham Greyhound Bus Station	No tags
	6:00pm	Downtown Greyhound Station	1d 2h	9:10pm	Durham Greyhound Bus Station	No tags
	10:00am	537-517 W. Jackson Blvd	1d 3h	2:10pm	Durham Greyhound Bus Station	No tags

Next departures for Chicago to Durham on September 18
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	6:00pm	Downtown Greyhound Station	1d 2h	9:10pm	Durham Greyhound Bus Station	Cheapest
	11:59pm	Downtown Greyhound Station	1d	1:15am	Durham Greyhound Bus Station	Fastest
Greyhound Lines, Inc. + FlixBus	6:55am	Downtown Greyhound Station	1d	8:30am	Durham Greyhound Bus Station	No tags
	2:45pm	Downtown Greyhound Station	1d	4:15pm	Durham Greyhound Bus Station	No tags
	6:40pm	Chicago 95Th & Dan Ryan	1d 1h	9:10pm	Durham Greyhound Bus Station	No tags

Compare 2 ways to go from Chicago to Durham.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$85 - $226	Average Duration1d 1h	CO₂ emissions 25kg CO₂e5 out of 5 stars	CheapestFastestMost eco-friendly
Train	Average Price$292 - $346	Average Duration1d 13h	CO₂ emissions 91kg CO₂e1 out of 5 stars

Busbud recommends taking the bus from Chicago to Durham

Among the sustainable travel choices, the bus stands out as the good way to reach Durham. The journey takes about 1 day, 1 hour 45 minutes and with fares starting at just $85, it presents an excellent value for a comfortable ride.

13bus per day

1d 1hAverage Duration

$85Cheapest ticket

25kgCO₂ emissions

Bus Chicago to Durham, NC, US: Trip Overview

Average ticket price$154

Average bus trip duration1d 1h

Number of daily buses13

Earliest bus departure12:30am

Distance612 miles (987 km)

Latest bus departure11:59pm

Compare bus companies

Greyhound

3.5/587,249 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/510,495 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Senda Diamante

Chicago to Durham Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Chicago to Durham.

Bus service from Chicago to Durham will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Durham from Chicago, we help you find what you're looking for based on how much of a budget you have.

Where are the popular stops in Chicago and Durham?

Stops in Chicago

A - Downtown Greyhound Station

B - Chicago O'Hare International Airport

C - Polk St & Canal St

D - Tornado Bus S Kedzie Ave

E - Cumberland CTA

F - Turimex California Ave

Stops in Durham

A - Durham Greyhound Bus Station

B - Compare Foods Durham

C - Durham Compare Foods Durham

D - Durham, NC

Frequently asked questions for your trip Chicago - Durham, NC, US

What is the travel distance from Chicago to Durham?
What are the departure and arrival stations when taking the bus from Chicago to Durham?
What are the best sights and things to do in Durham?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09/11

$83

09/12

$92

Today

$91

09/14

No data

09/15

$87

09/16

No data

09/17

$75

09/18

$76

The cheapest trip from Chicago to Durham, NC, US was searched and found on Sep 17, 2025 with a price of $75

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Durham, NC, US, as early as possible.

You can expect to pay from $75 to $206 for a bus ticket from Chicago to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $75 which is on 2025-09-17.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Chicago to Durham but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Chicago to Durham, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Chicago to Durham.

Tune out to the fine sounds of your best music playlist on your bus trip from Chicago to Durham while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Chicago to Durham, NC, US?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time1d 1h	Avg Price$154	Daily Departures13
Vehicle TypeTrain	Travel Time1d 13h	Avg Price$292	Daily Departures1

Will you be returning to Chicago by bus?

Bus from Durham, NC, US to Chicago

You can also go to Durham, NC, US by train

Train from Chicago to Durham, NC, US

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Chicago to Durham, NC, US

Next departures

Compare 2 ways to go from Chicago to Durham.

Bus Chicago to Durham, NC, US: Trip Overview

Compare bus companies

Chicago to Durham Bus

Where are the popular stops in Chicago and Durham?

Frequently asked questions for your trip Chicago - Durham, NC, US

What is the travel distance from Chicago to Durham?

What are the departure and arrival stations when taking the bus from Chicago to Durham?

What are the best sights and things to do in Durham?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Chicago to Durham, NC, US?

Will you be returning to Chicago by bus?

You can also go to Durham, NC, US by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago

Popular Buses Connecting Durham

Buses Leaving from Durham

Buses Going to Durham

Popular routes in this country

Popular airport transfers