Cheap buses leaving Friday
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: June 20 atDeparture city: ChicagoDeparture location: Downtown Greyhound StationArrival time: June 21 atDestination city: DurhamDestination location: Durham Greyhound Bus StationOperated by: FlixBus
Vehicle: BusDuration: - This trip is recommended because it is the: FastestDeparture time: June 20 atDeparture city: ChicagoDeparture location: Chicago 95Th & Dan RyanArrival time: June 21 atDestination city: DurhamDestination location: Durham Greyhound Bus StationOperated by: FlixBusVehicle: BusDuration:
- Departure time: June 20 atDeparture city: ChicagoDeparture location: Downtown Greyhound StationArrival time: June 21 atDestination city: DurhamDestination location: Durham Greyhound Bus StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: June 20 atDeparture city: ChicagoDeparture location: Downtown Greyhound StationArrival time: June 21 atDestination city: DurhamDestination location: Durham Greyhound Bus StationOperated by: FlixBusVehicle: BusDuration:
Last refresh of the prices: Yesterday at 6:20 AM CDT.
Prices and availability are subject to change.
Accepted payments
Compare 2 ways to go from Chicago to Durham
Busbud recommends taking the bus from Chicago to DurhamAmong the sustainable travel choices, the bus stands out as a good way to reach Durham. The journey takes about 1 day, 1 hour 35 minutes, and with fares starting at just US$94, it presents an excellent value for a comfortable ride.
Bus Chicago to Durham: Trip Overview
Compare bus companies
Chicago to Durham Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Chicago to Durham.
Bus service from Chicago to Durham will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Durham from Chicago, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Chicago and Durham?
Frequently asked questions on the trip Chicago - Durham (NC), US
How long is the trip from Chicago to Durham by bus?
The bus ride from Chicago to Durham takes 1d 1h, on average. For the shortest travel time, select the fastest bus available, which will take you to Durham in about 23h 50m.
What is the travel distance from Chicago to Durham?
Chicago and Durham are 999 km (620 miles) apart.
What are the departure and arrival locations for buses traveling from Chicago to Durham?
Buses departing from Downtown Greyhound Station in Chicago will take you to Durham Greyhound Bus Station in Durham.
What is the cheapest way to get from Chicago to Durham?
The least expensive option to go from Chicago to Durham would be going by bus. Starting at US$94, this bus is the most cost-effective option for your journey.
How much does the bus ticket cost from Chicago to Durham?
The bus from Chicago to Durham will cost you US$176, on average.
Is there an overnight bus from Chicago to Durham?
Yes! If you're heading from Chicago to Durham, you'll find buses departing until 11:59pm and arriving the next day.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Durham was searched and found on Jun 19, 2025 with a price of US$79To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Durham, as early as possible.
You can expect to pay from US$79 to US$249 for a bus ticket from Chicago to Durham based on the last 2 days. You can expect to find the cheapest price for the trip at US$79 which is on 2025-06-19.
Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Chicago to Durham but it'll also be endearing to native speakers who will surely appreciate your effort.
Much more than a mere vehicle taking you from Chicago to Durham, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Chicago to Durham.
Tune out to the fine sounds of your best music playlist on your bus trip from Chicago to Durham while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from Chicago to Durham?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.