Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Appleton | Gateway Station | Cheapest | |||||
 | Appleton | Gateway Station | Fastest | |||||
| Appleton | Gateway Station | No tags | |||||
| Appleton | Gateway Station | No tags | |||||
| Appleton | Gateway Station | No tags |
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Bus Appleton to St. Louis: Trip Overview
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Appleton to St. Louis Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Appleton to St. Louis.
We make sure you can find a bus service from Appleton to St. Louis from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from Appleton to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Frequently asked questions for your trip Appleton - St. Louis
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Appleton to St. Louis was searched and found on Aug 31, 2025 with a price of $94To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Appleton to St. Louis, as early as possible.
You can expect to pay from $94 to $392 for a bus ticket from Appleton to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $94 which is on 2025-08-31.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Appleton to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Appleton to St. Louis, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Appleton to St. Louis that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Appleton to St. Louis.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
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