Bus Tickets from Lafayette, IN to St Louis

Find affordable bus tickets from Lafayette, IN to St Louis with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJul 14
from $49
TomorrowJul 15
from $37
WedJul 16
from $43
ThuJul 17
from $39
FriJul 18
from $53
SatJul 19
SunJul 20
MonJul 21

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 15 at
    Departure city: Lafayette
    Departure location: Lafayette Bus Stop
    Arrival time: July 16 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 15 at
    Departure city: Lafayette
    Departure location: Lafayette Bus Stop
    Arrival time: July 15 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 15 at
    Departure city: Lafayette
    Departure location: Lafayette Bus Stop
    Arrival time: July 15 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 15 at
    Departure city: Lafayette
    Departure location: Lafayette Bus Stop
    Arrival time: July 15 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: July 15 at
    Departure city: Lafayette
    Departure location: Lafayette Bus Stop
    Arrival time: July 15 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Lafayette to St. Louis: Trip Overview

Average ticket price$51
Average bus trip duration9h 20m
Number of daily buses4
Earliest bus departure9:35am
Distance216 miles (347 km)
Latest bus departure9:25pm

Lafayette to St Louis Bus

With Busbud, comparing and booking tickets for a bus from Lafayette to St Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Lafayette to St Louis will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to St Louis from Lafayette, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Lafayette, IN - St Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/12
$41
07/13
No data
Today
$42
07/15
$30
07/16
$38
07/17
$33
07/18
$47
07/19
$48
busbud logoThe cheapest trip from Lafayette to St. Louis was searched and found on Jul 15, 2025 with a price of $30

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette to St. Louis, as early as possible.

You can expect to pay from $30 to $54 for a bus ticket from Lafayette to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $30 which is on 2025-07-15.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Lafayette to St Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Lafayette to St Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Lafayette to St Louis.

Make a music playlist for your bus ride from Lafayette to St Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Lafayette by bus?

Bus from Lafayette to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Lafayette

Buses Leaving from Lafayette

Buses Going to Lafayette

Popular Buses Connecting St. Louis

Buses Leaving from St. Louis

Buses Going to St. Louis