Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | Boston (South Station) | Cheapest | ||||
| Bus | Gateway Station | Boston (South Station) | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gateway Station | Boston (South Station) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gateway Station | Brookline | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gateway Station | 151 Steel Pl, Cambridge | No tags |
Last refresh of the prices: Today at 8:44 AM CST.
Compare 2 ways to travel from St. Louis to Boston
Among the sustainable travel choices, the Bus stands out as a good way to reach Boston. The journey takes about 1 day, 9 hours 35 minutes and with fares starting at just R 1 701, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Boston?
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C335 Grove St, Auburndale, MA 02466
- D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Compare bus companies
Frequently asked questions about travelling from St. Louis to Boston, MA, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from St. Louis to Boston?
The cheapest bus tickets from St. Louis to Boston start at R 1 701. The average price for this route is around R 3 129. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from St. Louis to Boston?
The average bus journey time from St. Louis to Boston is 1d 9h, covering a distance of 1668 km. The fastest bus gets you there in 1d 6h and is operated by Greyhound.
Which bus companies service the St. Louis to Boston route?
What is the earliest and latest departure time for the bus from St. Louis to Boston?
The earliest bus departs from St. Louis to Boston at 02:00. And the latest bus departs at 23:30.
What are the CO₂ emissions for the bus trip from St. Louis to Boston?
A bus trip from St. Louis to Boston produces an estimated 42 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from St. Louis to Boston?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from St. Louis to Boston?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from St. Louis to Boston?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to Boston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Boston, MA, US was searched and found on 17 Jan 2026 with a price of R 2 429To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Boston, MA, US as early as possible.
You can expect to pay from R 2 429 to R 3 497 for a bus ticket from St. Louis to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 429, which is on 2026-01-17.
What's the cheapest way to go from St. Louis to Boston, MA, US?
The Bus is the cheapest travel choice for this destination
