Bus Tickets from St. Louis to Boston, MA, US

Next departures

Next departures for St. Louis to Boston on September 21
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Gateway Station
151 Steel Pl, CambridgeCheapest
Greyhound Lines, Inc. + FlixBus
Gateway Station
Boston (South Station)Fastest
Greyhound Lines, Inc. + FlixBus
Gateway Station
Boston (South Station)No tags
Greyhound Lines, Inc.
Gateway Station
Boston (South Station)No tags
FlixBus + Greyhound Lines, Inc.
Gateway Station
Boston (South Station)No tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from St. Louis to Boston

Bus
Average PriceUS$82 - US$265Average Duration1d 11h
42kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$292 - US$529Average Duration1d 14h
151kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St. Louis to Boston

Among the sustainable travel choices, the bus stands out as a good way to reach Boston. The journey takes about 1 day, 11 hours 45 minutes, and with fares starting at just US$82, it presents an excellent value for a comfortable ride.

11bus per day
1d 11hAverage Duration
US$82Cheapest ticket
42kgCO₂ emissions

Bus St. Louis to Boston, MA, US: Trip Overview

Average Ticket PriceUS$117
Average Bus Trip Duration1d 11h
Number of daily buses11
Earliest bus departure2:00am
Distance1667 km
Latest bus departure11:30pm

St. Louis to Boston Bus

Busbud helps you find a bus from St. Louis to Boston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from St. Louis to Boston.

From cheap bus tickets to more luxurious buses travelling from St. Louis to Boston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip St. Louis - Boston, MA, US

  1. What is the travel distance from St. Louis to Boston?

    The distance between St. Louis and Boston is approximately 1669 km (1035 miles).

  2. What are the departure and arrival locations for buses traveling from St. Louis to Boston?

    Buses departing from Gateway Station in St. Louis will take you to Back Bay Station in Boston.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-18
US$177
09-19
US$131
Today
US$161
09-21
US$110
09-22
US$80
09-23
No data
09-24
US$75
09-25
US$117
busbud logoThe cheapest trip from St. Louis to Boston, MA, US was searched and found on Sep 24, 2025 with a price of US$75

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Boston, MA, US, as early as possible.

You can expect to pay from US$75 to US$177 for a bus ticket from St. Louis to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$75 which is on 2025-09-24.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between St. Louis and Boston!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from St. Louis to Boston.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St. Louis to Boston that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St. Louis to Boston.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from St. Louis to Boston, MA, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St. Louis by bus?

Bus from Boston, MA, US to St. Louis

You can also go to Boston, MA, US by train

Train from St. Louis to Boston, MA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting St. Louis

Buses Leaving from St. Louis

Buses Going to St. Louis

Popular Buses Connecting Boston

Buses Leaving from Boston

Buses Going to Boston