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Bus São Paulo to Santa Mercedes: Trip Overview

Average ticket priceUS$104
Average bus trip duration10h 30m
Number of daily buses1
Earliest bus departure21:30
Distance357 miles

São Paulo to Santa Mercedes Bus

With Busbud, comparing and booking tickets for a bus from São Paulo to Santa Mercedes is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from São Paulo to Santa Mercedes from the most reliable bus companies operating this trip.

Discover how much the bus trip from São Paulo to Santa Mercedes will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip São Paulo - Santa Mercedes

  1. How far is Santa Mercedes from São Paulo by coach?

    The journey from São Paulo to Santa Mercedes by coach covers an approximate distance of 361 miles (581 km).

  2. Is there a way to reach Santa Mercedes from São Paulo without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
20/06
US$55
21/06
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23/06
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busbud logoThe cheapest trip from São Paulo to Santa Mercedes was searched and found on 20 Jun 2025 with a price of US$55

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from São Paulo to Santa Mercedes as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from São Paulo to Santa Mercedes.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from São Paulo to Santa Mercedes, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from São Paulo to Santa Mercedes will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from São Paulo to Santa Mercedes, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to São Paulo by bus?

Bus from São Paulo to Santa Mercedes

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