Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Isernia | Rome Tiburtina Bus Station | CheapestFastest | ||||
| Bus | Isernia | Rome Fiumicino Airport | No tags | ||||
| Bus | Isernia | Rome Fiumicino Airport | No tags | ||||
| Bus | Isernia | Rome Tiburtina Bus Station | No tags |
Last refresh of the prices: Last Saturday at 20:44 CET.
Compare 3 ways to travel from Isernia to Rome
Among the sustainable travel choices, the carpool stands out as a good way to reach Rome. The journey takes about 2 hours and with fares starting at just £10, it presents an excellent value for a comfortable ride.
Where are the popular stops in Isernia and Rome?
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Compare bus companies
Based on 11633 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £14
Frequently asked questions about travelling by bus from Isernia to Rome
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Isernia to Rome?
The cheapest coach tickets from Isernia to Rome start from £14. The average price for this route is around £35. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Isernia to Rome?
The average bus journey time from Isernia to Rome is 9h 10m, covering a distance of 104 miles. The fastest bus can take you there in 2h 10m and is operated by FlixBus.
Which bus companies service the Isernia to Rome route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Isernia to Rome?
The earliest bus departs from Isernia to Rome at 11:25. And the latest bus departs at 15:50.
What are the CO₂ emissions for the bus trip from Isernia to Rome?
A bus journey from Isernia to Rome produces an estimated 4 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Isernia to Rome was searched and found on 20 Dec 2025 with a price of £12To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Isernia to Rome as early as possible.
You can expect to pay from £12 to £56 for a bus ticket from Isernia to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at £12, which is on 2025-12-20.
