Find coaches from Brussels to Prague

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Today2 Sept
from US$41
Tomorrow3 Sept
Thu4 Sept
from US$50
Fri5 Sept
from US$58
Sat6 Sept
Sun7 Sept
Mon8 Sept
from US$61
Tue9 Sept

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 4 September at
    Departure city: Brussels
    Departure location: Brussels South (Gare du Midi)
    Arrival time: 4 September at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 4 September at
    Departure city: Brussels
    Departure location: Brussels South (Gare du Midi)
    Arrival time: 5 September at
    Destination city: Prague
    Destination location: Florenc
    Operated by: RegioJetRegioJet
    Vehicle: BusDuration:
  • Departure time: 4 September at
    Departure city: Brussels
    Departure location: Brussels South (Gare du Midi)
    Arrival time: 5 September at
    Destination city: Prague
    Destination location: Florenc
    Operated by: RegioJetRegioJet
    Vehicle: BusDuration:
  • Departure time: 4 September at
    Departure city: Brussels
    Departure location: Brussels-North (Gare du Nord)
    Arrival time: 5 September at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: 4 September at
    Departure city: Brussels
    Departure location: Brussels-North (Gare du Nord)
    Arrival time: 5 September at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

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Compare 2 ways to travel from Brussels to Prague

Bus
Average priceUS$37 - US$233Average duration19h 15m
18kg CO₂e5 out of 5 stars
Cheapest
Train
Average priceUS$77 - US$389Average duration13h 3m
17kg CO₂e5 out of 5 stars
FastestMost eco-friendly
busbud logoBusbud recommends taking the train from Brussels to Prague

Among the sustainable travel choices, the train stands out as a good way to reach Prague. The journey takes about 13 hours 3 minutes and with fares starting at just US$77, it presents an excellent value for a comfortable ride.

12train per day
13h 3mAverage duration
US$77Cheapest ticket
17kgCO₂ emissions

Bus Brussels to Prague: Trip Overview

Average ticket priceUS$96
Average bus trip duration19h 15m
Number of daily buses32
Earliest bus departure00:45
Distance447 miles
Latest bus departure23:30

Brussels to Prague Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Brussels to Prague.

Bus service from Brussels to Prague will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Brussels to Prague, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Brussels - Prague

  1. How far is Prague from Brussels by coach?

    The distance between Brussels and Prague by coach is approximately 446 miles (719 km).

  2. Is there a way to reach Prague from Brussels without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
31/08
US$87
01/09
US$47
Today
US$38
03/09
No data
04/09
US$46
05/09
US$53
06/09
US$61
07/09
US$60
busbud logoThe cheapest trip from Brussels to Prague was searched and found on 2 Sept 2025 with a price of US$38

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Prague as early as possible.

You can expect to pay from US$38 to US$148 for a bus ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at US$46, which is on 2025-09-04.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Brussels to Prague but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Brussels to Prague, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Brussels to Prague that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Brussels to Prague, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Brussels to Prague?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Brussels by bus?

Bus from Prague to Brussels

You can also go to Prague by train

Train from Brussels to Prague

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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