How much is the bus ticket from Brussels to Prague?

The cheapest bus tickets from Brussels to Prague start from $64. The average price for this route is around $111. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Brussels to Prague?

The average bus travel time from Brussels to Prague is 18h 35m, covering a distance of 706 km. The quickest bus can get you there in 11h 55m and is operated by RegioJet .

Which bus companies service the Brussels to Prague route?

Several major bus companies operate on this route with 24 buses available per day, including services from FlixBus , BlaBlaCar Bus , RegioJet , Musil Tour .

What are the earliest and latest departure times for the bus from Brussels to Prague?

The earliest bus departs from Brussels to Prague at 12:45am. And the latest bus departs at 11:35pm.

What are the CO₂ emissions for the bus trip from Brussels to Prague?

A bus trip from Brussels to Prague generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Brussels to Prague?

According to Busbud customers, the highest-rated bus company on this route is RegioJet , with an average rating of 4.1 out of 5 stars based on 1069 reviews.

Which bus company has the best Wi-Fi from Brussels to Prague?

Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.

Which bus company has the best on-time performance from Brussels to Prague?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 4.0 out of 5 stars.

Which bus company has the cleanest buses from Brussels to Prague?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet , with a cleanliness rating of 4.4 out of 5 stars.

Bus Brussels to Prague from $62 | Refundable Tickets

Next bus departures

Next departures for Brussels to Prague on March 20
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:10pm	Brussels-South (Gare du Midi)	13h 35m	9:45am	Florenc	CheapestFastest
Bus	3:55pm	Brussels North Train Station	15h	6:55am	Prague (Central Bus Station Florenc)	No tags
Bus	5:10pm	Brussels North Train Station	17h	10:10am	Prague (Central Bus Station Florenc)	No tags
Bus	9:30pm	Brussels North Train Station	15h 10m	12:40pm	Prague (Central Bus Station Florenc)	No tags
Bus	10:55pm	Brussels North Train Station	18h 35m	5:30pm	Prague (Main Railway Station)	No tags

Next departures for Brussels to Prague on March 21
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:30pm	Brussels South (Gare du Midi)	17h 40m	4:10pm	Černý Most	Cheapest
Bus	9:30am	Brussels North Train Station	12h 50m	10:20pm	Prague (Central Bus Station Florenc)	Fastest
Bus	3:55pm	Brussels North Train Station	15h	6:55am	Prague (Central Bus Station Florenc)	No tags
Bus	6:30pm	Brussels North Train Station	14h 50m	9:20am	Prague (Central Bus Station Florenc)	No tags
Bus	9:30pm	Brussels North Train Station	15h 10m	12:40pm	Prague (Central Bus Station Florenc)	No tags

Next departures for Brussels to Prague on March 22
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	6:30pm	Brussels South (Gare du Midi)	11h 55m	6:25am	Florenc	CheapestFastest
Bus	9:30am	Brussels North Train Station	12h 50m	10:20pm	Prague (Central Bus Station Florenc)	No tags
Bus	3:55pm	Brussels North Train Station	15h	6:55am	Prague (Central Bus Station Florenc)	No tags
Bus	6:30pm	Brussels North Train Station	14h 50m	9:20am	Prague (Central Bus Station Florenc)	No tags
Bus	9:30pm	Brussels North Train Station	15h 10m	12:40pm	Prague (Central Bus Station Florenc)	No tags

Next departures for Brussels to Prague on March 23
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	2:20pm	Brussels-South (Gare du Midi)	19h 25m	9:45am	Florenc	CheapestFastest

Next departures for Brussels to Prague on March 24
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	9:30am	Brussels North Train Station	12h 50m	10:20pm	Prague (Central Bus Station Florenc)	CheapestFastest
Bus	3:55pm	Brussels North Train Station	15h	6:55am	Prague (Central Bus Station Florenc)	No tags
Bus	6:30pm	Brussels North Train Station	14h 50m	9:20am	Prague (Central Bus Station Florenc)	No tags
Bus	9:00pm	Brussels North Train Station	17h 20m	2:20pm	Prague (Central Bus Station Florenc)	No tags
Bus	10:30am	Brussels North Train Station	13h 55m	12:25am	Prague (Main Railway Station)	No tags

Next departures for Brussels to Prague on March 25
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	6:30pm	Brussels North Train Station	14h 50m	9:20am	Prague (Central Bus Station Florenc)	Cheapest
Bus	9:30am	Brussels North Train Station	12h 50m	10:20pm	Prague (Central Bus Station Florenc)	Fastest
Bus	9:00pm	Brussels North Train Station	17h 40m	2:40pm	Prague (Central Bus Station Florenc)	No tags
Bus	10:55pm	Brussels North Train Station	18h 35m	5:30pm	Prague (Main Railway Station)	No tags
Bus	9:00pm	Brussels North Train Station	18h	3:00pm	Prague (Main Station - parking)	No tags

Next departures for Brussels to Prague on March 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	9:30am	Brussels North Train Station	12h 50m	10:20pm	Prague (Central Bus Station Florenc)	Cheapest
Bus	6:30pm	Brussels South (Gare du Midi)	11h 55m	6:25am	Florenc	Fastest
Bus	4:30pm	Brussels North Train Station	18h 10m	10:40am	Prague (Central Bus Station Florenc)	No tags
Bus	9:30pm	Brussels North Train Station	15h 10m	12:40pm	Prague (Central Bus Station Florenc)	No tags
Bus	10:55pm	Brussels North Train Station	18h 35m	5:30pm	Prague (Main Railway Station)	No tags

Last refresh of the prices: Today at 5:38 AM CET.

Compare 2 ways to go from Brussels to Prague

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 18 hours 35 minutes, and with fares starting at just $64, it presents an excellent value for a comfortable ride.

24bus per day

18h 35mAverage Duration

706 kmDistance

18kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$64 - $268	Average Duration18h 35m	CO₂ emissions 18kg CO₂e
Train	Average Price$124 - $522	Average Duration15h 29m	CO₂ emissions 17kg CO₂e

Where are the popular stops in Brussels and Prague?

Stops in Brussels

A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium
Visit page
B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
Visit page
C
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
D
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
Visit page

Stops in Prague

A
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
B
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
Visit page
C
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
Visit page
D
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Visit page
E
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page

Compare bus companies

FlixBus

3.5/512,335 reviews

Staff4.2

Timeliness4

Cleanliness4.1

Wi‑Fi2.7

BlaBlaCar Bus

3.5/511,528 reviews

Staff4.4

Timeliness3.7

Cleanliness4.3

Wi‑Fi2.6

RegioJet

4/51,069 reviews

Staff4.5

Timeliness3.9

Cleanliness4.4

Wi‑Fi3.8

Musil Tour

CZ bus companies:FlixBus, Greyhound, BlaBlaCar Bus, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Brussels to Prague by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Brussels to Prague?
The cheapest bus tickets from Brussels to Prague start from $64. The average price for this route is around $111. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brussels to Prague?
The average bus travel time from Brussels to Prague is 18h 35m, covering a distance of 706 km. The quickest bus can get you there in 11h 55m and is operated by RegioJet.
Which bus companies service the Brussels to Prague route?
Several major bus companies operate on this route with 24 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet, Musil Tour.
What are the earliest and latest departure times for the bus from Brussels to Prague?
The earliest bus departs from Brussels to Prague at 12:45am. And the latest bus departs at 11:35pm.
What are the CO₂ emissions for the bus trip from Brussels to Prague?
A bus trip from Brussels to Prague generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Brussels to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1069 reviews.
Which bus company has the best Wi-Fi from Brussels to Prague?
Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.
Which bus company has the best on-time performance from Brussels to Prague?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Brussels to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

03-18

No data

03-19

$116

Today

$80

03-21

$95

03-22

$83

03-23

$100

03-24

$62

03-25

$83

The cheapest trip from Brussels to Prague was searched and found on Mar 24, 2026 with a price of $62

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Prague, as early as possible.

You can expect to pay from $62 to $233 for a bus ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $62 which is on 2026-03-24.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.