Bus Tickets from Santa Ana, US to San Ysidro, CA

Next departures

Next departures for Santa Ana to San Ysidro on September 21
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
UC Irvine (Crawford Hall)
San Ysidro Bus terminalCheapest
Los Limousines
Santa Ana E Santa Ana Blvd
San Ysidro Greyhound Bus StationFastest
Greyhound Lines, Inc.
Anaheim Regional Transportation Intermodal Center
San Ysidro Bus terminalNo tags
FlixBus
Santa Ana Bus Station
San Ysidro Bus terminalNo tags
Los Limousines
Santa Ana E Santa Ana Blvd
San Ysidro Greyhound Bus StationNo tags

Accepted payments

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Bus Santa Ana, US to San Ysidro, CA: Trip Overview

Average Ticket PriceUS$44
Average Bus Trip Duration3h
Number of daily buses24
Earliest bus departure5:55am
Distance155 km
Latest bus departure10:15pm

Santa Ana to San Ysidro Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santa Ana to San Ysidro.

We make sure you can find a bus service from Santa Ana to San Ysidro from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Santa Ana to San Ysidro, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santa Ana, US - San Ysidro, CA

  1. What is the travel distance from Santa Ana to San Ysidro?

    The distance between Santa Ana and San Ysidro is around 154 km (96 miles).

  2. What are the departure and arrival locations for buses traveling from Santa Ana to San Ysidro?

    Buses traveling this route start their trip at Santa Ana Greyhound Bus Station, in Santa Ana, and end it at San Ysidro Greyhound Bus Station, in San Ysidro.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-18
US$19
09-19
US$18
Today
US$18
09-21
US$20
09-22
US$17
09-23
US$17
09-24
US$17
09-25
US$17
busbud logoThe cheapest trip from Santa Ana, US to San Ysidro, CA was searched and found on Sep 25, 2025 with a price of US$17

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to San Ysidro, CA, as early as possible.

You can expect to pay from US$17 to US$40 for a bus ticket from Santa Ana, US to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at US$17 which is on 2025-09-25.

Usually Los Limousines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santa Ana to San Ysidro but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santa Ana to San Ysidro, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Ana to San Ysidro that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Santa Ana to San Ysidro while indulging in miles on end of beautiful scenic views.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Santa Ana, US by bus?

Bus from San Ysidro, CA to Santa Ana, US

Why choose Busbud?

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