Bus Tickets from Santa Ana (CA), US to San Ysidro (CA)

Find affordable bus tickets from Santa Ana (CA), US to San Ysidro (CA) with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TomorrowJun 10
from US$43
WedJun 11
from US$43
ThuJun 12
from US$43
FriJun 13
from US$43
SatJun 14
from US$43
SunJun 15
from US$43
MonJun 16
from US$43
TueJun 17

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 10 at
    Departure city: Santa Ana
    Departure location: Santa Ana E Santa Ana Blvd
    Arrival time: June 10 at
    Destination city: San Ysidro
    Destination location: San Ysidro Greyhound Bus Station
    Operated by: Los LimousinesLos Limousines
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 10 at
    Departure city: Santa Ana
    Departure location: Santa Ana E Santa Ana Blvd
    Arrival time: June 10 at
    Destination city: San Ysidro
    Destination location: San Ysidro Greyhound Bus Station
    Operated by: Los LimousinesLos Limousines
    Vehicle: BusDuration:
  • Departure time: June 10 at
    Departure city: Santa Ana
    Departure location: Santa Ana E Santa Ana Blvd
    Arrival time: June 10 at
    Destination city: San Ysidro
    Destination location: San Ysidro Greyhound Bus Station
    Operated by: Los LimousinesLos Limousines
    Vehicle: BusDuration:
  • Departure time: June 10 at
    Departure city: Santa Ana
    Departure location: Santa Ana E Santa Ana Blvd
    Arrival time: June 10 at
    Destination city: San Ysidro
    Destination location: San Ysidro Greyhound Bus Station
    Operated by: Los LimousinesLos Limousines
    Vehicle: BusDuration:
  • Departure time: June 10 at
    Departure city: Santa Ana
    Departure location: Santa Ana E Santa Ana Blvd
    Arrival time: June 10 at
    Destination city: San Ysidro
    Destination location: San Ysidro Greyhound Bus Station
    Operated by: Los LimousinesLos Limousines
    Vehicle: BusDuration:

Last refresh of the prices: Today at 9:34 AM PDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Santa Ana to San Ysidro: Trip Overview

Average Ticket PriceUS$42
Average Bus Trip Duration5h 15m
Number of daily buses12
Earliest bus departure5:55am
Distance155 km
Latest bus departure10:15pm

Santa Ana to San Ysidro Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santa Ana to San Ysidro.

We make sure you can find a bus service from Santa Ana to San Ysidro from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Santa Ana to San Ysidro, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santa Ana (CA), US - San Ysidro (CA)

  1. How long is the trip from Santa Ana to San Ysidro by bus?

    The typical travel time from Santa Ana to San Ysidro by bus is around 5h 15m. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 1h 45m.

  2. What is the travel distance from Santa Ana to San Ysidro?

    The distance between Santa Ana and San Ysidro is around 154 km (96 miles).

  3. What are the departure and arrival locations for buses traveling from Santa Ana to San Ysidro?

    Buses traveling this route start their trip at Santa Ana Greyhound Bus Station, in Santa Ana, and end it at San Ysidro Greyhound Bus Station, in San Ysidro.

  4. What is the cheapest way to go from Santa Ana to San Ysidro?

    If you're on a budget, consider traveling by bus to San Ysidro from Santa Ana; it tends to be more affordable. The ticket price for this bus starts at US$41, making this your best choice for this trip.

  5. How much does the bus ticket cost from Santa Ana to San Ysidro?

    Taking the bus from Santa Ana to San Ysidro costs on average US$42.

  6. Is it possible to do a day trip from Santa Ana to San Ysidro?

    Yes! Taking a day trip from Santa Ana to San Ysidro is very much possible. You can expect the round-trip to take approximately 3h 30m in total travel time. Be sure to check the departure and arrival times before booking to ensure you'll have enough time to explore San Ysidro.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-07
US$39
06-08
US$38
Today
US$39
06-10
US$38
06-11
US$39
06-12
US$39
06-13
US$39
06-14
US$38
busbud logoThe cheapest trip from Santa Ana to San Ysidro was searched and found on Jun 8, 2025 with a price of US$38

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana to San Ysidro, as early as possible.

You can expect to pay from US$38 to US$39 for a bus ticket from Santa Ana to San Ysidro based on the last 2 days. You can expect to find the cheapest price for the trip at US$38 which is on 2025-06-10.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santa Ana to San Ysidro but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santa Ana to San Ysidro, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Ana to San Ysidro that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Santa Ana to San Ysidro while indulging in miles on end of beautiful scenic views.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Santa Ana by bus?

Bus from Santa Ana to San Ysidro

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

Popular Buses Connecting Santa Ana

Buses Leaving from Santa Ana

Buses Going to Santa Ana

Popular Buses Connecting San Ysidro

Buses Leaving from San Ysidro

Buses Going to San Ysidro