Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Florenc | Rome Tiburtina Bus Station | CheapestFastest |
Last refresh of the prices: Today at 12:01 AM CET.
Compare 2 ways to go from Prague to Rome
Among the sustainable travel choices, the carpool stands out as a good way to reach Rome. The journey takes about 13 hours 20 minutes, and with fares starting at just $96, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$71 - $410 | Average Duration1d | 23kg CO₂e | ||
Carpool | Average Price$96 - $96 | Average Duration13h 20m | 39kg CO₂e |
Where are the popular stops in Prague and Rome?
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- BTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - DChlumecká, 198 00 Praha 20, Czech Republic
- EKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
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Frequently asked questions about travelling from Prague to Rome by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Prague to Rome?
The cheapest bus tickets from Prague to Rome start from $71. The average price for this route is around $187. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Prague to Rome?
The average bus travel time from Prague to Rome is 1d , covering a distance of 917 km. The quickest bus can get you there in 19h 15m and is operated by FlixBus.
Which bus companies service the Prague to Rome route?
Several major bus companies operate on this route with 40 buses available per day, including services from FlixBus, RegioJet, BlaBlaCar Bus.
What are the earliest and latest departure times for the bus from Prague to Rome?
The earliest bus departs from Prague to Rome at 2:30am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Prague to Rome?
A bus trip from Prague to Rome generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Prague to Rome?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1062 reviews.
Which bus company has the best Wi-Fi from Prague to Rome?
Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.
Which bus company has the best on-time performance from Prague to Rome?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Prague to Rome?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Rome was searched and found on Dec 30, 2025 with a price of $126To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Rome, as early as possible.
You can expect to pay from $126 to $353 for a bus ticket from Prague to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $126 which is on 2025-12-30.
