Bus Tickets from Prague to Rome

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TodayJun 21
from $109
TomorrowJun 22
from $105
MonJun 23
from $83
TueJun 24
from $86
WedJun 25
from $86
ThuJun 26
FriJun 27
from $86
SatJun 28
from $85

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 22 at
    Departure city: Prague
    Departure location: PRG Airport
    Arrival time: June 23 at
    Destination city: Rome
    Destination location: Rome Anagnina
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 22 at
    Departure city: Prague
    Departure location: Prague (Main Station - parking)
    Arrival time: June 23 at
    Destination city: Rome
    Destination location: Rome Tiburtina Bus Station
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: June 22 at
    Departure city: Prague
    Departure location: Prague (Central Bus Station Florenc)
    Arrival time: June 23 at
    Destination city: Rome
    Destination location: Aeroporto Ciampino Airport (CIA)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: June 22 at
    Departure city: Prague
    Departure location: Prague (Central Bus Station Florenc)
    Arrival time: June 24 at
    Destination city: Rome
    Destination location: Aeroporto Ciampino Airport (CIA)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: June 22 at
    Departure city: Prague
    Departure location: Prague (Main Station - parking)
    Arrival time: June 23 at
    Destination city: Rome
    Destination location: Aeroporto Ciampino Airport (CIA)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Accepted payments

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Bus Prague to Rome: Trip Overview

Average ticket price$121
Average bus trip duration1d
Number of daily buses50.53623188405798
Earliest bus departure2:30am
Distance572 miles (921 km)
Latest bus departure11:50pm

Prague to Rome Bus

Busbud helps you find a bus from Prague to Rome. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Prague to Rome.

Whether it is cheap bus tickets or more luxurious buses going to Rome from Prague, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Prague - Rome

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/19
$117
06/20
$133
Today
$106
06/22
$101
06/23
$80
06/24
$83
06/25
$82
06/26
$131
busbud logoThe cheapest trip from Prague to Rome was searched and found on Jun 23, 2025 with a price of $80

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Rome, as early as possible.

You can expect to pay from $80 to $280 for a bus ticket from Prague to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $80 which is on 2025-06-23.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Prague and Rome!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Prague to Rome.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Prague to Rome.

Tune out to the fine sounds of your best music playlist on your bus trip from Prague to Rome while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Prague by bus?

Bus from Prague to Rome

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