Bus Tickets from Prague to Frankfurt am Main

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TueSep 2
from US$44
TodaySep 3
from US$39
TomorrowSep 4
from US$38
FriSep 5
from US$43
SatSep 6
from US$39
SunSep 7
from US$44
MonSep 8
from US$34
TueSep 9
from US$32

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: September 3 at
    Departure city: Prague
    Departure location: Prague (Central Bus Station Florenc)
    Arrival time: September 3 at
    Destination city: Frankfurt am Main
    Destination location: Frankfurt Hbf
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: September 3 at
    Departure city: Prague
    Departure location: Florenc
    Arrival time: September 4 at
    Destination city: Frankfurt am Main
    Destination location: Frankfurt - Main bus station
    Operated by: RegioJetRegioJet
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Prague
    Departure location: Florenc
    Arrival time: September 4 at
    Destination city: Frankfurt am Main
    Destination location: Frankfurt - Main bus station
    Operated by: RegioJetRegioJet
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Prague
    Departure location: Prague (Central Bus Station Florenc)
    Arrival time: September 3 at
    Destination city: Frankfurt am Main
    Destination location: FRA Frankfurt airport
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Prague
    Departure location: Prague (Central Bus Station Florenc)
    Arrival time: September 3 at
    Destination city: Frankfurt am Main
    Destination location: FRA Frankfurt airport
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Accepted payments

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Compare 3 ways to go from Prague to Frankfurt am Main

Bus
Average PriceUS$27 - US$140Average Duration8h 40m
10kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average PriceUS$32 - US$270Average Duration8h 24m
10kg CO₂e5 out of 5 stars
Carpool
Average PriceUS$22 - US$37Average Duration5h 20m
17kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends carpooling from Prague to Frankfurt am Main

Among the sustainable travel choices, the carpool stands out as a good way to reach Frankfurt am Main. The journey takes about 5 hours 20 minutes, and with fares starting at just US$22, it presents an excellent value for a comfortable ride.

3carpool per day
5h 20mAverage Duration
US$22Cheapest ticket
17kgCO₂ emissions

Bus Prague to Frankfurt am Main: Trip Overview

Average Ticket PriceUS$43
Average Bus Trip Duration8h 40m
Number of daily buses28
Earliest bus departure3:30am
Distance418 km
Latest bus departure11:05pm

Prague to Frankfurt am Main Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Prague to Frankfurt am Main.

We make it our job to connect you with the most dependable bus companies that cover bus service from Prague to Frankfurt am Main.

Whether it is cheap bus tickets or more luxurious buses going to Frankfurt am Main from Prague, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Prague - Frankfurt am Main

  1. How far is Prague from Frankfurt am Main?

    It's about 410 km (254 miles) from Prague to Frankfurt am Main.

  2. What are the departure and arrival locations for buses traveling from Prague to Frankfurt am Main?

    Buses departing from Zličín in Prague will take you to Frankfurt Airport in Frankfurt am Main.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-01
US$43
09-02
US$40
Today
US$35
09-04
US$34
09-05
US$39
09-06
US$35
09-07
US$40
09-08
US$31
busbud logoThe cheapest trip from Prague to Frankfurt am Main was searched and found on Sep 8, 2025 with a price of US$31

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Frankfurt am Main, as early as possible.

You can expect to pay from US$31 to US$79 for a bus ticket from Prague to Frankfurt am Main based on the last 2 days. You can expect to find the cheapest price for the trip at US$31 which is on 2025-09-08.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Prague to Frankfurt am Main but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Prague to Frankfurt am Main.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Prague to Frankfurt am Main.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Prague to Frankfurt am Main.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Prague by bus?

Bus from Frankfurt am Main to Prague

You can also go to Frankfurt am Main by train

Train from Prague to Frankfurt am Main

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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