Bus Tickets from Frankfurt am Main to Prague

Next departures

Next departures for Frankfurt am Main to Prague on September 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
RegioJet
Frankfurt - Main bus station
FlorencCheapestFastest
Flixbus
Frankfurt Hbf
PRG AirportNo tags
Flixtrain + Flixbus
Südbahnhof
Prague (Central Bus Station Florenc)No tags
Flixbus
Frankfurt Hbf
PRG AirportNo tags
Flixtrain + Flixbus
Südbahnhof
Prague (Main Station - parking)No tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 3 ways to go from Frankfurt am Main to Prague

Bus
Average PriceUS$29 - US$104Average Duration8h 55m
10kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$32 - US$330Average Duration8h 13m
10kg CO₂e5 out of 5 stars
Carpool
Average PriceUS$30 - US$58Average Duration5h 30m
17kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Frankfurt am Main to Prague

Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours 30 minutes, and with fares starting at just US$30, it presents an excellent value for a comfortable ride.

2carpool per day
5h 30mAverage Duration
US$30Cheapest ticket
17kgCO₂ emissions

Bus Frankfurt am Main to Prague: Trip Overview

Average Ticket PriceUS$42
Average Bus Trip Duration8h 55m
Number of daily buses25
Earliest bus departure12:25am
Distance400 km
Latest bus departure11:59pm

Frankfurt am Main to Prague Bus

With Busbud, comparing and booking tickets for a bus from Frankfurt am Main to Prague is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Frankfurt am Main to Prague will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Frankfurt am Main to Prague, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Frankfurt am Main - Prague

  1. What is the travel distance from Frankfurt am Main to Prague?

    The distance covered from Frankfurt am Main to Prague is 410 km (254 miles).

  2. What are the departure and arrival locations for buses traveling from Frankfurt am Main to Prague?

    Buses traveling this route start their trip at Frankfurt Airport, in Frankfurt am Main, and end it at Florenc, in Prague.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-01
US$40
09-02
US$36
Today
US$31
09-04
US$34
09-05
US$39
09-06
US$33
09-07
US$41
09-08
US$29
busbud logoThe cheapest trip from Frankfurt am Main to Prague was searched and found on Sep 8, 2025 with a price of US$29

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frankfurt am Main to Prague, as early as possible.

You can expect to pay from US$29 to US$99 for a bus ticket from Frankfurt am Main to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at US$29 which is on 2025-09-08.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Frankfurt am Main to Prague.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Frankfurt am Main to Prague, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Frankfurt am Main to Prague that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Frankfurt am Main to Prague.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Frankfurt am Main by bus?

Bus from Prague to Frankfurt am Main

You can also go to Prague by train

Train from Frankfurt am Main to Prague

Why choose Busbud?

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