Previously seen trips
One passenger / one way
- Departure time: August 23 atDeparture city: Port Saint LucieDeparture location: Port St. Lucie (Park & Ride)Arrival time: August 23 atDestination city: CharlestonDestination location: 4565 Gaynor Ave, North CharlestonOperated by: FlixBus
Vehicle: BusDuration:
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Bus Port Saint Lucie to Charleston, SC, US: Trip Overview
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Based on 10288 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at US$103
Port Saint Lucie to Charleston Bus
With Busbud, comparing and booking tickets for a bus from Port Saint Lucie to Charleston is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Port Saint Lucie to Charleston will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from Port Saint Lucie to Charleston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Port Saint Lucie and Charleston?
Frequently asked questions on the trip Port Saint Lucie - Charleston, SC, US
What is the travel distance from Port Saint Lucie to Charleston?
The distance covered from Port Saint Lucie to Charleston is 613 km (380 miles).
What are the departure and arrival locations for buses traveling from Port Saint Lucie to Charleston?
Buses traveling this route start their trip at Port St Lucie Mobil Gas Bus Stop, in Port Saint Lucie, and end it at Charleston Bus Station, in Charleston.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Port Saint Lucie to Charleston, SC, US was searched and found on Aug 28, 2025 with a price of US$95To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Port Saint Lucie to Charleston, SC, US, as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Port Saint Lucie to Charleston.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Port Saint Lucie to Charleston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Port Saint Lucie to Charleston that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Port Saint Lucie to Charleston, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Top travelled bus routes
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Popular Buses Connecting Port Saint Lucie
Buses Leaving from Port Saint Lucie
- Bus from Port Saint Lucie to West Palm Beach
- Bus Port Saint Lucie - Miami
- Port Saint Lucie - Fort Lauderdale
- Bus from Port Saint Lucie to Kissimmee
- Bus Port Saint Lucie - Orlando
- Port Saint Lucie - Jacksonville
- Bus from Port Saint Lucie to Boston
- Bus Port Saint Lucie - Gainesville
- Port Saint Lucie - Sarasota
- Bus from Port Saint Lucie to Tampa
- Bus Port Saint Lucie - Atlanta
- Port Saint Lucie - Daytona Beach
- Bus from Port Saint Lucie to Fort Pierce
- Bus Port Saint Lucie - Boca Raton
- Port Saint Lucie - Boynton Beach
Buses Going to Port Saint Lucie
- Bus from Fort Pierce to Port Saint Lucie
- Bus Fort Lauderdale - Port Saint Lucie
- Tampa - Port Saint Lucie
- Bus from Jupiter to Port Saint Lucie
- Bus Orlando - Port Saint Lucie
- West Palm Beach - Port Saint Lucie
- Bus from Miami to Port Saint Lucie
- Bus Jacksonville - Port Saint Lucie
- Valdosta - Port Saint Lucie
- Bus from Lakeland to Port Saint Lucie
- Bus Vero Beach - Port Saint Lucie
- Key West - Port Saint Lucie
- Bus from New York City to Port Saint Lucie
- Bus Austin - Port Saint Lucie
- New Haven - Port Saint Lucie
Popular Buses Connecting Charleston
Buses Leaving from Charleston
- Bus from Charleston to Baltimore
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- Charleston - Atlanta
- Bus from Charleston to Fort Worth
- Bus Charleston - Miami
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- Bus Charleston - Orlando
- Charleston - Las Vegas
- Bus from Charleston to Springfield
- Bus Charleston - Wilson
- Charleston - Greensboro
- Bus from Charleston to Providence
- Bus Charleston - Greenville
- Charleston - Raleigh
Buses Going to Charleston
- Bus from Baltimore to Charleston
- Bus Boston - Charleston
- Greenville - Charleston
- Bus from Nashville to Charleston
- Bus Raleigh - Charleston
- Los Angeles - Charleston
- Bus from Savannah to Charleston
- Bus Buffalo - Charleston
- Austin - Charleston
- Bus from Orlando to Charleston
- Bus Spartanburg - Charleston
- Philadelphia - Charleston
- Bus from Bangor to Charleston
- Bus Atlanta - Charleston
- Las Vegas - Charleston
Popular routes in this country
- Bus from Washington to New York City
- Bus Boston - New York City
- New York City - Boston
- Bus from Buffalo to New York City
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- Albany - New York City
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- Bus from Miami to Orlando
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- Syracuse - New York City