Bus Tickets from Jacksonville, FL to Port Saint Lucie

Find affordable bus tickets from Jacksonville, FL to Port Saint Lucie with flexible options. Book your trip now

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TodayJun 28
TomorrowJun 29
from US$44
MonJun 30
from US$44
TueJul 1
from US$44
WedJul 2
from US$45
ThuJul 3
from US$45
FriJul 4
from US$46
SatJul 5

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 29 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: June 29 at
    Destination city: Port Saint Lucie
    Destination location: Port St Lucie (Park & Ride)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 29 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: June 30 at
    Destination city: Port Saint Lucie
    Destination location: Port St Lucie (Park & Ride)
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: June 29 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: June 30 at
    Destination city: Port Saint Lucie
    Destination location: Port St Lucie (Park & Ride)
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: June 29 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: June 30 at
    Destination city: Port Saint Lucie
    Destination location: Port St Lucie (Park & Ride)
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Monday at 12:13 AM EDT.

Prices and availability are subject to change.

Accepted payments

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  • China Union Pay
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  • Google Pay

Bus Jacksonville to Port Saint Lucie: Trip Overview

Average Ticket PriceUS$48
Average Bus Trip Duration6h 40m
Number of daily buses2
Earliest bus departure9:00am
Distance362 km
Latest bus departure9:10pm

Jacksonville to Port Saint Lucie Bus

With Busbud, comparing and booking tickets for a bus from Jacksonville to Port Saint Lucie is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Jacksonville to Port Saint Lucie will be provided by the most trusted bus companies.

Discover how much the bus trip from Jacksonville to Port Saint Lucie will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Jacksonville, FL - Port Saint Lucie

  1. What is the distance between Jacksonville and Port Saint Lucie?

    The distance covered from Jacksonville to Port Saint Lucie is 362 km (225 miles).

  2. What are the departure and arrival locations for buses traveling from Jacksonville to Port Saint Lucie?

    Buses traveling this route start their trip at Jacksonville Amtrak Station, in Jacksonville, and end it at Port Saint Lucie - Wendys, in Port Saint Lucie.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-26
US$34
06-27
US$37
Today
US$37
06-29
US$36
06-30
US$36
07-01
US$36
07-02
US$37
07-03
US$37
busbud logoThe cheapest trip from Jacksonville to Port Saint Lucie was searched and found on Jun 26, 2025 with a price of US$34

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville to Port Saint Lucie, as early as possible.

You can expect to pay from US$34 to US$67 for a bus ticket from Jacksonville to Port Saint Lucie based on the last 2 days. You can expect to find the cheapest price for the trip at US$36 which is on 2025-06-29.

Usually FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Jacksonville to Port Saint Lucie.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Jacksonville to Port Saint Lucie, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Jacksonville to Port Saint Lucie will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Jacksonville to Port Saint Lucie, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Jacksonville by bus?

Bus from Jacksonville to Port Saint Lucie

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