Bus Tickets from Greenville, SC to Cincinnati

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Previously seen trips

One passenger / one way

  • Departure time: August 31 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: September 1 at
    Destination city: Cincinnati
    Destination location: Cincinnati Bus Station
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 19 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: September 20 at
    Destination city: Cincinnati
    Destination location: Cincinnati Bus Station
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: October 12 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: October 13 at
    Destination city: Cincinnati
    Destination location: Cincinnati Bus Station
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: October 12 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: October 13 at
    Destination city: Cincinnati
    Destination location: Cincinnati Bus Station
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: October 25 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: October 26 at
    Destination city: Cincinnati
    Destination location: Cincinnati Bus Station
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:

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Compare 2 ways to go from Greenville to Cincinnati

Bus
Average PriceUS$75 - US$163Average Duration12h 40m
13kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$165 - US$275Average Duration23h 8m
46kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Cincinnati

Among the sustainable travel choices, the bus stands out as a good way to reach Cincinnati. The journey takes about 12 hours 40 minutes, and with fares starting at just US$75, it presents an excellent value for a comfortable ride.

1bus per day
12h 40mAverage Duration
US$75Cheapest ticket
13kgCO₂ emissions

Bus Greenville, SC to Cincinnati: Trip Overview

Average Ticket PriceUS$101
Average Bus Trip Duration12h 40m
Number of daily buses1
Earliest bus departure2:45pm
Distance523 km
Latest bus departure7:45pm

Greenville to Cincinnati Bus

Busbud helps you find a bus from Greenville to Cincinnati. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Greenville to Cincinnati from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to Cincinnati will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville, SC - Cincinnati

  1. How far is Greenville from Cincinnati?

    It's about 514 km (319 miles) from Greenville to Cincinnati.

  2. What are the departure and arrival locations for buses traveling from Greenville to Cincinnati?

    Buses traveling this route start their trip at Guadalajara Supermarket Bus Stop, in Greenville, and end it at Greyhound Station, in Cincinnati.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-01
US$155
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busbud logoThe cheapest trip from Greenville, SC to Cincinnati was searched and found on Sep 1, 2025 with a price of US$155

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Cincinnati, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and Cincinnati!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Cincinnati, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Cincinnati will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Cincinnati while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Greenville, SC to Cincinnati?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from Cincinnati to Greenville, SC

You can also go to Cincinnati by train

Train from Greenville, SC to Cincinnati

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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