Bus Tickets from Florianópolis to Santiago, BR

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TodayJun 23
from US$67
TomorrowJun 24
WedJun 25
ThuJun 26
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MonJun 30

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 23 at
    Departure city: Florianópolis
    Departure location: Rodoviária de Florianópolis
    Arrival time: June 24 at
    Destination city: Santiago
    Destination location: Estação Rodoviária De Santiago
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:
  • Departure time: June 23 at
    Departure city: Florianópolis
    Departure location: Rodoviária de Florianópolis
    Arrival time: June 24 at
    Destination city: Santiago
    Destination location: Estação Rodoviária De Santiago
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:

Last refresh of the prices: Last Thursday at 3:59 PM -03.

Prices and availability are subject to change.

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Bus Florianópolis to Santiago: Trip Overview

Average Ticket PriceUS$65
Average Bus Trip Duration14h 45m
Number of daily buses1
Earliest bus departure10:00pm
Distance641 km

Florianópolis to Santiago Bus

Busbud helps you find a bus from Florianópolis to Santiago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Florianópolis to Santiago from the most reliable bus companies operating this trip.

Discover how much the bus trip from Florianópolis to Santiago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Florianópolis - Santiago, BR

  1. What is the distance between Florianópolis and Santiago?

    It's about 643 km (399 miles) from Florianópolis to Santiago.

  2. What are the departure and arrival locations for buses traveling from Florianópolis to Santiago?

    Buses departing from Rodoviária de Florianópolis in Florianópolis will take you to Santiago Onibus in Santiago.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-21
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06-22
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Today
US$57
06-24
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06-25
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06-26
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06-27
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06-28
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busbud logoThe cheapest trip from Florianópolis to Santiago was searched and found on Jun 23, 2025 with a price of US$57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florianópolis to Santiago, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Florianópolis and Santiago!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Florianópolis to Santiago, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Florianópolis to Santiago will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Florianópolis to Santiago while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Florianópolis by bus?

Bus from Florianópolis to Santiago

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