Cheap buses leaving tomorrow
One passenger / one way
- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: Fastest
- Departure time: August 3 atDeparture city: FlorenceDeparture location: Bus stationArrival time: August 4 atDestination city: HarrisburgDestination location: HarrisburgOperated by: FlixBus
Vehicle: BusDuration:
Last refresh of the prices: Last Monday at 10:51 AM EDT.
Prices and availability are subject to change.
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Compare 2 ways to go from Florence to Harrisburg
Busbud recommends taking the train from Florence to HarrisburgAmong the sustainable travel choices, the train stands out as a good way to reach Harrisburg. The journey takes about 14 hours 54 minutes, and with fares starting at just US$178, it presents an excellent value for a comfortable ride.
Bus Florence, SC, US to Harrisburg: Trip Overview
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Florence to Harrisburg Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Harrisburg.
We make sure you can find a bus service from Florence to Harrisburg from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Harrisburg from Florence, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Florence and Harrisburg?
Frequently asked questions on the trip Florence, SC, US - Harrisburg
What is the distance between Florence and Harrisburg?
It's about 718 km (446 miles) from Florence to Harrisburg.
What are the departure and arrival locations for buses traveling from Florence to Harrisburg?
Buses departing from Florence Bus Station in Florence will take you to Harrisburg Bieber Greyhound Station in Harrisburg.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Harrisburg was searched and found on Aug 1, 2025 with a price of US$147To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Harrisburg, as early as possible.
You can expect to pay from US$147 to US$170 for a bus ticket from Florence, SC, US to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at US$170 which is on 2025-08-03.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Harrisburg but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Florence to Harrisburg, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Florence to Harrisburg.
Tune out to the fine sounds of your best music playlist on your bus trip from Florence to Harrisburg while indulging in miles on end of beautiful scenic views.
Did you know?
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
What's the cheapest way to go from Florence, SC, US to Harrisburg?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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