Bus Tickets from Denver to Panama City, US

Find affordable bus tickets from Denver to Panama City, US with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Previously seen trips

One passenger / one way

  • Departure time: September 20 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: September 22 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: October 20 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: October 22 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: December 10 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: December 12 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: January 13 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: January 15 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: January 24 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: January 26 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Denver to Panama City, US: Trip Overview

Average Ticket PriceUS$251
Average Bus Trip Duration1d 12h
Number of daily buses2
Earliest bus departure7:50am
Distance2043 km
Latest bus departure7:25pm

Denver to Panama City Bus

Busbud helps you find a bus from Denver to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Denver to Panama City from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Denver to Panama City, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Denver - Panama City, US

  1. What is the travel distance from Denver to Panama City?

    The distance between Denver and Panama City is around 2053 km (1273 miles).

  2. What are the departure and arrival locations for buses traveling from Denver to Panama City?

    Buses traveling this route start their trip at Union Station, in Denver, and end it at Panama City Greyhound Bus Station, in Panama City.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-30
US$228
08-31
No data
Today
No data
09-02
No data
09-03
No data
09-04
No data
09-05
No data
09-06
No data
busbud logoThe cheapest trip from Denver to Panama City, US was searched and found on Aug 30, 2025 with a price of US$228

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Denver to Panama City, US, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Denver and Panama City!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Denver to Panama City, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Denver to Panama City that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Denver to Panama City while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Denver by bus?

Bus from Panama City, US to Denver

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Denver

Buses Leaving from Denver

Buses Going to Denver

Popular Buses Connecting Panama City

Buses Leaving from Panama City

Buses Going to Panama City