Bus Tickets from Charleston (WV), US to Greenville (SC)

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Compare 2 ways to go from Charleston to Greenville

Bus
Average PriceUS$127 - US$194Average Duration9h 20m
10kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$169 - US$220Average Duration20h 53m
36kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Charleston to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 9 hours 20 minutes, and with fares starting at just US$127, it presents an excellent value for a comfortable ride.

1bus per day
9h 20mAverage Duration
US$127Cheapest ticket
10kgCO₂ emissions

Bus Charleston to Greenville: Trip Overview

Average Ticket PriceUS$158
Average Bus Trip Duration9h 20m
Number of daily buses1
Earliest bus departure5:15am
Distance397 km

Charleston to Greenville Bus

Busbud helps you find a bus from Charleston to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Charleston to Greenville will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Charleston to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Charleston (WV), US - Greenville (SC)

  1. How long does it take to get to Greenville from Charleston by bus?

    The typical travel time from Charleston to Greenville by bus is around 9h 20m. For the shortest travel time, select the fastest bus available, which will take you to Greenville in about 9h 20m.

  2. What is the distance between Charleston and Greenville?

    The distance between Charleston and Greenville is around 396 km (246 miles).

  3. What are the departure and arrival locations for buses traveling from Charleston to Greenville?

    Buses traveling this route start their trip at Charleston Greyhound Bus Station, in Charleston, and end it at Guadalajara Supermarket Bus Stop, in Greenville.

  4. What is the cheapest way to go from Charleston to Greenville?

    The least expensive option to go from Charleston to Greenville would be going by bus. Starting at US$127, this bus is the most cost-effective option for your journey.

  5. How much is the bus from Charleston to Greenville?

    The bus fare from Charleston to Greenville is approximately US$158.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
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06-15
US$117
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busbud logoThe cheapest trip from Charleston to Greenville was searched and found on Jun 15, 2025 with a price of US$117

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston to Greenville, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Charleston and Greenville!

Much more than a mere vehicle taking you from Charleston to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Charleston to Greenville that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Charleston to Greenville.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Charleston to Greenville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Charleston by bus?

Bus from Charleston to Greenville

You can also go to Greenville by train

Train from Charleston to Greenville

Why choose Busbud?

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