Trains tickets from Milwaukee to St. Louis

Discover your next train travel journey from Milwaukee to St. Louis and book online with ease

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJul 28
from $91
TomorrowJul 29
from $81
WedJul 30
from $81
ThuJul 31
from $81
FriAug 1
from $91
SatAug 2
from $86
SunAug 3
from $99
MonAug 4
from $78

Trains leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: July 29 at
    Departure city: Milwaukee
    Departure location: MKE Airport - Trains
    Arrival time: July 29 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: July 29 at
    Departure city: Milwaukee
    Departure location: MKE Airport - Trains
    Arrival time: July 29 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: July 29 at
    Departure city: Milwaukee
    Departure location: MKE Airport - Trains
    Arrival time: July 29 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: July 29 at
    Departure city: Milwaukee
    Departure location: MKE Airport - Trains
    Arrival time: July 29 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: July 29 at
    Departure city: Milwaukee
    Departure location: MKE Airport - Trains
    Arrival time: July 29 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Milwaukee to St. Louis.

Bus
Average Price$47 - $129Average Duration10h 45m
13kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$51 - $137Average Duration8h 25m
47kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Milwaukee to St. Louis

Among the sustainable travel choices, the train stands out as the good way to reach St. Louis. The journey takes about 8 hours 25 minutes and with fares starting at just $51, it presents an excellent value for a comfortable ride.

9train per day
8h 25mAverage Duration
$51Cheapest ticket
47kgCO₂ emissions

Train Milwaukee to St. Louis: Trip Overview

Please note, this information is subject to change.

Average ticket price$68
Average train trip duration8h 25m
Number of daily trains9
Earliest train departure6:15am
Distance321 miles (517 km)
Latest train departure3:10pm

Milwaukee to St. Louis Train

With Busbud, comparing and booking tickets for a train from Milwaukee to St. Louis is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.

We make it our job to connect you with the most dependable companies that offer train service from Milwaukee to St. Louis.

Discover how much the train trip from Milwaukee to St. Louis will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.

Frequently asked questions for your trip Milwaukee - St. Louis

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/26
$86
07/27
$375
Today
$86
07/29
$77
07/30
$77
07/31
$77
08/01
$86
08/02
$81
busbud logoThe cheapest trip from Milwaukee to St. Louis was searched and found on Jul 29, 2025 with a price of $77

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Milwaukee to St. Louis, as early as possible.

You can expect to pay from $77 to $375 for a train ticket from Milwaukee to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $77 which is on 2025-07-29.

About Train Travel

Train Travel Tips

Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Milwaukee to St. Louis is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.

Whether you take a regional or high-speed train to St. Louis, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

With up to 30x less CO2 emissions for your train journey between Milwaukee and St. Louis, the train is an ecological alternative to flights or personal cars.

Create your own real life musical score by curating a personalized train travel playlist - the perfect accompaniment to your bus ride from Milwaukee to St. Louis.

Did you know?

Railway companies played a major role as early as 1883 in the use of time zones as we know them today.

You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.

Japanese trains are always on time, it is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologize to each passenger.

Will you be returning to Milwaukee by train?

Train from St. Louis to Milwaukee

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular train departures from Milwaukee

Popular train departures to Milwaukee

Continue your journey from St. Louis