Next departures to Detroit
One passenger / one way
- This trip is recommended because it is: Cheapest + FastestDeparture time: August 1 atDeparture city: GreenvilleDeparture location: Greenville StationArrival time: August 2 atDestination city: DetroitDestination location: Amtrak StationOperated by: Amtrak
Vehicle: BusDuration: - Departure time: August 1 atDeparture city: GreenvilleDeparture location: Greenville StationArrival time: August 2 atDestination city: DetroitDestination location: Amtrak StationOperated by: AmtrakVehicle: BusDuration:
- Departure time: August 1 atDeparture city: GreenvilleDeparture location: Greenville StationArrival time: August 2 atDestination city: DetroitDestination location: Amtrak StationOperated by: AmtrakVehicle: BusDuration:
- Departure time: August 1 atDeparture city: GreenvilleDeparture location: Greenville StationArrival time: August 2 atDestination city: DetroitDestination location: Amtrak StationOperated by: AmtrakVehicle: BusDuration:
- Departure time: August 1 atDeparture city: GreenvilleDeparture location: Greenville StationArrival time: August 2 atDestination city: DetroitDestination location: Amtrak StationOperated by: AmtrakVehicle: BusDuration:
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Compare 2 ways to go from Greenville to Detroit.
Busbud recommends taking the bus from Greenville to DetroitAmong the sustainable travel choices, the bus stands out as the good way to reach Detroit. The journey takes about 19 hours 45 minutes and with fares starting at just $89, it presents an excellent value for a comfortable ride.
Train Greenville, SC to Detroit, MI: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5349 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $393
Greenville to Detroit Train
With Busbud, comparing and booking tickets for a train from Greenville to Detroit is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
Train service from Greenville to Detroit will be provided by the most trusted companies.
From train tickets to high-end trains trip from Greenville to Detroit, we offer a wide range of train services to best suit your needs depending on how much your budget is.
Frequently asked questions for your trip Greenville, SC - Detroit, MI
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Detroit, MI was searched and found on Aug 1, 2025 with a price of $455To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville, SC to Detroit, MI, as early as possible.
You can expect to pay from $455 to $1,562 for a train ticket from Greenville, SC to Detroit, MI based on the last 2 days. You can expect to find the cheapest price for the trip at $455 which is on 2025-08-01.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Greenville to Detroit is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
No matter if you plan to take a regional or high-speed train to Detroit, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.
The train emits up to 30x less CO2 for a trip between Greenville and Detroit compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.
Create your own real life musical score by curating a personalized train travel playlist - the perfect accompaniment to your bus ride from Greenville to Detroit.
Did you know?
One of the deepest train stations in the world is in Kiev. Located at a depth of 105 m, it was designed in this way to serve as a shelter in the event of an attack. The second deepest station is in China. Badaling station is located 60 m under the Great Wall of China!
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
Top Traveled Train Routes
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Popular train departures from Greenville
Popular train departures to Greenville
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