Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Depew Station | Chicago (Union Station), IL | CheapestFastest | |||||
| Depew Station | Chicago (Union Station), IL | No tags |
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Compare 2 ways to go from Buffalo to Chicago.
Busbud recommends taking the bus from Buffalo to ChicagoAmong the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 15 hours 30 minutes and with fares starting at just $54, it presents an excellent value for a comfortable ride.
Train Buffalo, NY to Chicago: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5457 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $56
Buffalo to Chicago Train
Busbud helps you find a train from Buffalo to Chicago. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.
We make sure you can find a train service from Buffalo to Chicago from the most reliable train companies operating this trip.
From train tickets to high-end trains trip from Buffalo to Chicago, we offer a wide range of train services to best suit your needs depending on how much your budget is.
Where are the popular train stations and stops in Buffalo, NY and Chicago?
Frequently asked questions for your trip Buffalo, NY - Chicago
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Chicago was searched and found on Sep 12, 2025 with a price of $129To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo, NY to Chicago, as early as possible.
You can expect to pay from $129 to $1,442 for a train ticket from Buffalo, NY to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $129 which is on 2025-09-18.
About Train Travel
Train Travel Tips
There are many train stations in the world, check it station pages on Busbud to get all information you need.
Regional train? High-speed train? Whichever train to Chicago you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
The train emits up to 30x less CO2 for a trip between Buffalo and Chicago compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.
Make a music playlist for your train ride from Buffalo to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Japanese trains are always on time, it is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologize to each passenger.
The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while traveling more than 17,000 km.
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
Top Traveled Train Routes
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