Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | South Station (Train Terminal) | Greenville Station | Cheapest | |||||
| Boston Route 128, MA | Greenville Station | Fastest | |||||
| South Station (Train Terminal) | Greenville Station | No tags | |||||
| South Station (Train Terminal) | Greenville Station | No tags | |||||
| Boston Route 128, MA | Greenville Station | No tags |
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Compare 2 ways to go from Boston to Greenville.
Busbud recommends taking the bus from Boston to GreenvilleAmong the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 23 hours 5 minutes and with fares starting at just $91, it presents an excellent value for a comfortable ride.
Train Boston, MA, US to Greenville, SC: Trip Overview
Please note, this information is subject to change.
Train Companies
Boston to Greenville Train
Busbud helps you find a train from Boston to Greenville. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.
Train service from Boston to Greenville will be provided by the most trusted companies.
Whether it is train tickets or first class train tickets going to Greenville from Boston, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Boston, MA, US - Greenville, SC
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Greenville, SC was searched and found on Sep 3, 2025 with a price of $264To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Boston, MA, US to Greenville, SC, as early as possible.
You can expect to pay from $264 to $870 for a train ticket from Boston, MA, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $264 which is on 2025-09-09.
About Train Travel
Train Travel Tips
There are many train stations in the world, check it station pages on Busbud to get all information you need.
No matter if you plan to take a regional or high-speed train to Greenville, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.
By choosing the train between Boston and Greenville, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Tune out to the fine sounds of your best music playlist on your train trip from Boston to Greenville while indulging in miles on end of beautiful scenic views.
Did you know?
The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while traveling more than 17,000 km.
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
Top Traveled Train Routes
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Trains Connecting Boston
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