Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Amtrak Station | Greenville Station | CheapestFastest | ||||
| Train | Amtrak Station | Greenville Station | No tags | ||||
| Train | Amtrak Station | Greenville Station | No tags |
Last refresh of the prices: Last Friday at 1:12 PM EST.
Compare 2 ways to go from Detroit to Greenville
Among the sustainable travel choices, the Bus stands out as the good way to reach Greenville. The journey takes about 1 day, 3 hours 25 minutes and with fares starting at just $87, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5727 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $222
Frequently asked questions about traveling from Detroit, MI to Greenville, SC by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Detroit to Greenville?
The cheapest train tickets from Detroit to Greenville start from $222. The average price for this train route is around $476. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Detroit to Greenville?
The average train ride duration from Detroit to Greenville is 1d 19h, covering a distance of 519 miles (837 km). The quickest train can get you there in 1d 19h and is operated by Amtrak.
Which train operators service the Detroit to Greenville route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Detroit to Greenville?
The earliest train departs from Detroit to Greenville at 9:35am. And the latest train departs at 9:35am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Greenville, SC was searched and found on Jan 15, 2026 with a price of $213To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Detroit, MI to Greenville, SC, as early as possible.
You can expect to pay from $213 to $1,133 for a train ticket from Detroit, MI to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $213 which is on 2026-01-15.
