Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Wytheville Bus Station | 199 Spring Garden St. | No tags | ||||
FlixBus + Greyhound | Bus | Wytheville Bus Station | Philadelphia, 199 Spring Garden St | No tags | ||||
Greyhound + FlixBus | Bus | Wytheville Bus Station | Cherry Hill Mall | No tags | ||||
FlixBus + Greyhound | Bus | Wytheville Bus Station | Philadelphia, 199 Spring Garden St | No tags | ||||
| Bus | Wytheville Bus Station | 199 Spring Garden St. | No tags |
Get from Wytheville to Philadelphia
The journey takes about 17 hours 55 minutes and with fares starting at just $122, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Wytheville to Philadelphia, PA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Wytheville to Philadelphia?
The cheapest bus tickets from Wytheville to Philadelphia start from $122. The average price for this route is around $177. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Wytheville to Philadelphia?
The average bus trip duration from Wytheville to Philadelphia is 17h 55m, covering a distance of 371 miles (599 km). The quickest bus can get you there in 12h 20m and is operated by Greyhound.
Which bus companies service the Wytheville to Philadelphia route?
Several major train operators operate on this route with 7 trains available per day.
What is the earliest and latest departure time for the bus from Wytheville to Philadelphia?
The earliest bus departs from Wytheville to Philadelphia at 2:45am. And the latest bus departs at 8:55am.
What are the CO₂ emissions for the bus trip from Wytheville to Philadelphia?
A bus trip from Wytheville to Philadelphia generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wytheville to Philadelphia, PA was searched and found on Jan 16, 2026 with a price of $120To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wytheville to Philadelphia, PA, as early as possible.
