Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Based on 5418 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $123
With Busbud, comparing and booking tickets for a bus from Winston-Salem to Orlando is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Winston-Salem to Orlando.
Whether it is cheap bus tickets or more luxurious buses going to Orlando from Winston-Salem, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Winston-Salem and Orlando?
Frequently asked questions for your trip Winston-Salem - Orlando
What is the travel distance from Winston-Salem to Orlando?
Winston-Salem and Orlando are 527 miles (849 km) apart.
What are the departure and arrival stations when taking the bus from Winston-Salem to Orlando?
The majority of buses traveling from Winston-Salem to Orlando start their journey at Winston Salem Greyhound Bus Station and wind up at Orlando Bus Station. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Orlando?
Once in Orlando, you can start exploring the city and discover its surroundings. The top sights and things to do are Sports & Adventure, Ritz Carlton Golf Club, ESPN Wide World of Sports Complex, John F. Kennedy Space Center and Harry P. Leu Gardens.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
08/22
No data
08/23
$101
Today
$93
08/25
$82
08/26
$79
08/27
$83
08/28
$95
08/29
$114
The cheapest trip from Winston-Salem to Orlando was searched and found on Aug 26, 2025 with a price of $79
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Winston-Salem to Orlando, as early as possible.
You can expect to pay from $79 to $374 for a bus ticket from Winston-Salem to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $79 which is on 2025-08-26.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Winston-Salem to Orlando.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Winston-Salem to Orlando.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Winston-Salem to Orlando.
Tune out to the fine sounds of your best music playlist on your bus trip from Winston-Salem to Orlando while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.