Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Newark (DE) | 4565 Gaynor Ave, North Charleston | Cheapest | |||||
Greyhound Lines, Inc. + FlixBus | Wilmington Bus Station | 4565 Gaynor Ave, North Charleston | Fastest | |||||
Greyhound Lines, Inc. + FlixBus | Wilmington Bus Station | 4565 Gaynor Ave, North Charleston | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Wilmington Bus Station | 4565 Gaynor Ave, North Charleston | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Newark (DE) | 4565 Gaynor Ave, North Charleston | No tags |
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Compare 2 ways to go from Wilmington to Charleston.
Busbud recommends taking the train from Wilmington to CharlestonAmong the sustainable travel choices, the train stands out as the good way to reach Charleston. The journey takes about 11 hours 39 minutes and with fares starting at just $93, it presents an excellent value for a comfortable ride.
Bus Wilmington, DE to Charleston, SC, US: Trip Overview
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Wilmington to Charleston Bus
Busbud helps you find a bus from Wilmington to Charleston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Wilmington to Charleston.
Whether it is cheap bus tickets or more luxurious buses going to Charleston from Wilmington, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Wilmington and Charleston?
Frequently asked questions for your trip Wilmington, DE - Charleston, SC, US
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wilmington, DE to Charleston, SC, US was searched and found on Sep 4, 2025 with a price of $79To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Charleston, SC, US, as early as possible.
You can expect to pay from $79 to $135 for a bus ticket from Wilmington, DE to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $79 which is on 2025-09-04.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wilmington and Charleston!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Wilmington to Charleston.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Wilmington to Charleston.
Tune out to the fine sounds of your best music playlist on your bus trip from Wilmington to Charleston while indulging in miles on end of beautiful scenic views.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from Wilmington, DE to Charleston, SC, US?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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Popular Buses Connecting Wilmington
Buses Leaving from Wilmington
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Buses Going to Wilmington
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- Bus Philadelphia - Wilmington
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- Bus from Washington to Wilmington
- Bus Newark - Wilmington
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Popular Buses Connecting Charleston
Buses Leaving from Charleston
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- Bus Charleston - Washington
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Buses Going to Charleston
- Bus from Baltimore to Charleston
- Bus Boston - Charleston
- Greenville - Charleston
- Bus from Nashville to Charleston
- Bus Raleigh - Charleston
- Wilmington - Charleston
- Bus from Savannah to Charleston
- Bus Atlanta - Charleston
- Orlando - Charleston
- Bus from New York City to Charleston
- Bus Miami - Charleston
- Charlotte - Charleston
- Bus from Jacksonville to Charleston
- Bus Washington - Charleston
- Tampa - Charleston
Popular routes in this country
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