Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tupelo (Brothers Quick Stop) | 459 N Burdick St | CheapestFastest |
Last refresh of the prices: Last Monday at 2:32 PM CST.
Get from Tupelo to Kalamazoo
The journey takes about 21 hours 20 minutes and with fares starting at just $164, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Tupelo to Kalamazoo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tupelo to Kalamazoo?
The cheapest bus tickets from Tupelo to Kalamazoo start from $164. The average price for this route is around $173. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tupelo to Kalamazoo?
The average bus trip duration from Tupelo to Kalamazoo is 21h 20m, covering a distance of 581 miles (937 km). The quickest bus can get you there in 21h 20m and is operated by Greyhound.
Which bus companies service the Tupelo to Kalamazoo route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Tupelo to Kalamazoo?
The earliest bus departs from Tupelo to Kalamazoo at 10:55am. And the latest bus departs at 9:35pm.
What are the CO₂ emissions for the bus trip from Tupelo to Kalamazoo?
A bus trip from Tupelo to Kalamazoo generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Kalamazoo was searched and found on Jan 14, 2026 with a price of $157To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Kalamazoo, as early as possible.
