Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | Altoona Station | CheapestFastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Gateway Station | Altoona Station | No tags |
Last refresh of the prices: Last Friday at 5:14 PM CST.
Compare 2 ways to go from St. Louis to Altoona
Among the sustainable travel choices, the Bus stands out as a good way to reach Altoona. The journey takes about 21 hours 45 minutes and with fares starting at just $126, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from St. Louis to Altoona by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from St. Louis to Altoona?
The cheapest bus tickets from St. Louis to Altoona start from $126. The average price for this route is around $204. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Altoona?
The average bus trip duration from St. Louis to Altoona is 21h 45m, covering a distance of 641 miles (1033 km). The quickest bus can get you there in 21h 45m and is operated by Greyhound.
Which bus companies service the St. Louis to Altoona route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from St. Louis to Altoona?
The earliest bus departs from St. Louis to Altoona at 1:55pm. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from St. Louis to Altoona?
A bus trip from St. Louis to Altoona generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Altoona was searched and found on Feb 5, 2026 with a price of $111To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Altoona, as early as possible.
You can expect to pay from $111 to $208 for a bus ticket from St. Louis to Altoona based on the last 2 days. You can expect to find the cheapest price for the trip at $111 which is on 2026-02-05.
What's the cheapest way to go from St. Louis to Altoona?
The Bus is the cheapest travel choice for this destination
