Bus Tickets from Spartanburg to Chicago

Find affordable bus tickets from Spartanburg to Chicago with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Next departures

Next departures for Spartanburg to Chicago on September 16
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Spartanburg
Chicago 95Th & Dan RyanCheapestFastest
Greyhound Lines, Inc. + FlixBus
Spartanburg
Downtown Greyhound StationNo tags
Greyhound Lines, Inc.
Spartanburg
Downtown Greyhound StationNo tags
FlixBus + Greyhound Lines, Inc.
Spartanburg
Downtown Greyhound StationNo tags
FlixBus + Greyhound Lines, Inc.
Spartanburg
537-517 W. Jackson BlvdNo tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Spartanburg to Chicago.

Bus
Average Price$88 - $229Average Duration20h 30m
22kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$191 - $478Average Duration1d 6h
83kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Spartanburg to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 20 hours 30 minutes and with fares starting at just $88, it presents an excellent value for a comfortable ride.

11bus per day
20h 30mAverage Duration
$88Cheapest ticket
22kgCO₂ emissions

Bus Spartanburg to Chicago: Trip Overview

Average ticket price$119
Average bus trip duration20h 30m
Number of daily buses11
Earliest bus departure6:05am
Distance554 miles (893 km)
Latest bus departure9:00pm

Spartanburg to Chicago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Spartanburg to Chicago.

We make it our job to connect you with the most dependable bus companies that cover bus service from Spartanburg to Chicago.

Whether it is cheap bus tickets or more luxurious buses going to Chicago from Spartanburg, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Spartanburg - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/11
$113
09/12
$96
Today
$115
09/14
No data
09/15
No data
09/16
$91
09/17
$90
09/18
No data
busbud logoThe cheapest trip from Spartanburg to Chicago was searched and found on Sep 17, 2025 with a price of $90

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Spartanburg to Chicago, as early as possible.

You can expect to pay from $90 to $115 for a bus ticket from Spartanburg to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $90 which is on 2025-09-17.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Spartanburg to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Spartanburg to Chicago.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Spartanburg to Chicago.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Spartanburg to Chicago.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Spartanburg to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Spartanburg by bus?

Bus from Chicago to Spartanburg

You can also go to Chicago by train

Train from Spartanburg to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Spartanburg

Buses Leaving from Spartanburg

Buses Going to Spartanburg

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago