Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Greyhound Station | Des Moines | CheapestFastest |
Last refresh of the prices: Last Wednesday at 7:50 PM PST.
Get from Seattle to Des Moines
The journey takes about 2 days, 8 hours 10 minutes and with fares starting at just $228, it presents an excellent value for a comfortable ride.
Where are the popular stops in Seattle and Des Moines?
Stops in Seattle
- A503 S Royal Brougham Way, Seattle, WA 98134, USA
- C
Washington State Convention Center
705 Pike St, Seattle WA 98101, USA, , Pick-up is at the Charter Bus Loading Zone on 8th Avenue at the corner of 8th Ave. and Pike Street. - D2001 W Garfield St, Seattle WA 98119, USA
- E
Pier 66
2203 Alaskan Way, Seattle WA 98121, USA - F
International District
700-822 5th Ave S, Seattle, WA 98104, USA
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Seattle to Des Moines by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Seattle to Des Moines?
The cheapest bus tickets from Seattle to Des Moines start from $228. The average price for this route is around $228. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Seattle to Des Moines?
The average bus trip duration from Seattle to Des Moines is 2d 8h, covering a distance of 1460 miles (2354 km). The quickest bus can get you there in 2d 8h and is operated by Greyhound.
Which bus companies service the Seattle to Des Moines route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Seattle to Des Moines?
The earliest bus departs from Seattle to Des Moines at 10:50pm. And the latest bus departs at 10:50pm.
What are the CO₂ emissions for the bus trip from Seattle to Des Moines?
A bus trip from Seattle to Des Moines generates an estimated 59 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Seattle to Des Moines was searched and found on Jan 2, 2026 with a price of $248To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Seattle to Des Moines, as early as possible.
