Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Santa Ana Bus Station | Calexico Bus Station | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Santa Ana Bus Station | Calexico Bus Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Anaheim Regional Transportation Intermodal Center | Calexico Bus Station | No tags |
Last refresh of the prices: Yesterday at 6:46 PM PST.
Get from Santa Ana to Calexico
The journey takes about 8 hours 35 minutes and with fares starting at just $53, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santa Ana and Calexico?
Stops in Santa Ana
- A
Santa Ana Greyhound Bus Station
1000 E Santa Ana Blvd, Santa Ana, CA 92701 - B
602 S Main St
602 S Main St, Santa Ana, CA 92701, USA
Stops in Calexico
- A
Calexico Bus Station
123 E 1st St, Calexico, CA 92231 - B
Calexico
498 W 2nd St, Calexico, CA 92231, USA
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Frequently asked questions about traveling from Santa Ana, US to Calexico by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santa Ana to Calexico?
The cheapest bus tickets from Santa Ana to Calexico start from $53. The average price for this route is around $82. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santa Ana to Calexico?
The average bus trip duration from Santa Ana to Calexico is 8h 35m, covering a distance of 159 miles (255 km). The quickest bus can get you there in 4h 55m and is operated by Greyhound.
Which bus companies service the Santa Ana to Calexico route?
What is the earliest and latest departure time for the bus from Santa Ana to Calexico?
The earliest bus departs from Santa Ana to Calexico at 7:55am. And the latest bus departs at 10:15am.
What are the CO₂ emissions for the bus trip from Santa Ana to Calexico?
A bus trip from Santa Ana to Calexico generates an estimated 6 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Santa Ana to Calexico?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11828 reviews.
Which bus company has the best Wi-Fi from Santa Ana to Calexico?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Santa Ana to Calexico?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Santa Ana to Calexico?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Ana, US to Calexico was searched and found on Jan 10, 2026 with a price of $48To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to Calexico, as early as possible.
You can expect to pay from $48 to $48 for a bus ticket from Santa Ana, US to Calexico based on the last 2 days. You can expect to find the cheapest price for the trip at $48 which is on 2026-01-10.
