How much is the bus ticket from San Antonio to Indianapolis?

The cheapest bus tickets from San Antonio to Indianapolis start from $117. The average price for this route is around $193. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from San Antonio to Indianapolis?

The average bus trip duration from San Antonio to Indianapolis is 1d 6h, covering a distance of 998 miles (1609 km). The quickest bus can get you there in 1d 2h and is operated by Greyhound .

Which bus companies service the San Antonio to Indianapolis route?

Several major bus companies operate on this route with 13 buses available per day, including services from Greyhound , Valley Transit , FlixBus .

What is the earliest and latest departure time for the bus from San Antonio to Indianapolis?

The earliest bus departs from San Antonio to Indianapolis at 1:30am. And the latest bus departs at 9:15pm.

What are the CO₂ emissions for the bus trip from San Antonio to Indianapolis?

A bus trip from San Antonio to Indianapolis generates an estimated 40 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from San Antonio to Indianapolis?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87435 reviews.

Which bus company has the best Wi-Fi from San Antonio to Indianapolis?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from San Antonio to Indianapolis?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from San Antonio to Indianapolis?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus San Antonio to Indianapolis from $127 | Refundable Tickets

Next bus departures

Next departures for San Antonio to Indianapolis on December 30
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus	Bus	7:15pm	San Antonio Bus Station	1d 12h	8:25am	Downtown Transit Center	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	1d 2h	4:45am	Indianapolis Bus Station	Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	6:05am	San Antonio Bus Station	1d 5h	12:05pm	Indianapolis Bus Station	No tags
Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus	Bus	1:30am	San Antonio Bus Station	1d 5h	8:25am	Downtown Transit Center	No tags
	Bus	12:35pm	San Antonio Bus Station	1d 3h	4:35pm	Indianapolis Bus Station	No tags

Next departures for San Antonio to Indianapolis on December 31
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus	Bus	1:30am	San Antonio Bus Station	1d 12h	2:35pm	Indianapolis Northeast	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	1d 2h	4:45am	Indianapolis Bus Station	Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	6:05am	San Antonio Bus Station	1d 5h	12:05pm	Indianapolis Bus Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 6h	4:45am	Indianapolis Bus Station	No tags
Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus	Bus	1:30am	San Antonio Bus Station	1d 5h	8:25am	Downtown Transit Center	No tags

Next departures for San Antonio to Indianapolis on January 3
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	7:45am	Pearl District	1d 23h	8:25am	Downtown Transit Center	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	1d 2h	4:45am	Indianapolis Bus Station	Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	6:05am	San Antonio Bus Station	1d 5h	12:05pm	Indianapolis Bus Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:30am	San Antonio Bus Station	1d 6h	2:30pm	Indianapolis Bus Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 6h	4:45am	Indianapolis Bus Station	No tags

Last refresh of the prices: Yesterday at 6:19 PM CST.

Compare 2 ways to go from San Antonio to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 1 day, 6 hours 30 minutes and with fares starting at just $117, it presents an excellent value for a comfortable ride.

13bus per day

1d 6hAverage Duration

998 milesDistance

40kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$117 - $570	Average Duration1d 6h	CO₂ emissions 40kg CO₂e
Train	Average Price$156 - $1,038	Average Duration1d 16h	CO₂ emissions 146kg CO₂e

Where are the popular stops in San Antonio and Indianapolis?

Stops in San Antonio

A
San Antonio Bus Station
500 N St Mary's St, San Antonio, TX 78205, USA
Visit page
B
Tornado I-35
7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
Visit page
C
San Antonio, TX
165 Bowie St, San Antonio, 78205
Visit page
D
4407 S PanAm Expy #101
4407 S PanAm Expy #101, San Antonio, TX 78225, USA
Visit page

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Compare bus companies

Greyhound

3.5/587,458 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Valley Transit

3/537 reviews

Staff3.9

Timeliness3.4

Cleanliness2.8

Wifi2.8

FlixBus

3.5/511,791 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from San Antonio, US to Indianapolis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from San Antonio to Indianapolis?
The cheapest bus tickets from San Antonio to Indianapolis start from $117. The average price for this route is around $193. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Antonio to Indianapolis?
The average bus trip duration from San Antonio to Indianapolis is 1d 6h, covering a distance of 998 miles (1609 km). The quickest bus can get you there in 1d 2h and is operated by Greyhound.
Which bus companies service the San Antonio to Indianapolis route?
Several major bus companies operate on this route with 13 buses available per day, including services from Greyhound, Valley Transit, FlixBus.
What is the earliest and latest departure time for the bus from San Antonio to Indianapolis?
The earliest bus departs from San Antonio to Indianapolis at 1:30am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from San Antonio to Indianapolis?
A bus trip from San Antonio to Indianapolis generates an estimated 40 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from San Antonio to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from San Antonio to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from San Antonio to Indianapolis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Antonio to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/26

$288

12/27

$322

Today

No data

12/29

$246

12/30

$240

12/31

$193

The cheapest trip from San Antonio, US to Indianapolis was searched and found on Dec 31, 2025 with a price of $193

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Indianapolis, as early as possible.

You can expect to pay from $193 to $322 for a bus ticket from San Antonio, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $193 which is on 2025-12-31.