Bus Tickets from Rochester, NY, US to St. Louis

TodayJul 31
TomorrowAug 1
from $154
SatAug 2
SunAug 3
MonAug 4
TueAug 5
WedAug 6
ThuAug 7
from $176

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: August 1 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: August 2 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: August 2 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: August 3 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Rochester to St. Louis.

Bus
Average Price$153 - $235Average Duration1d 4h
29kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$193 - $860Average Duration20h 38m
107kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Rochester to St. Louis

Among the sustainable travel choices, the train stands out as the good way to reach St. Louis. The journey takes about 20 hours 38 minutes and with fares starting at just $193, it presents an excellent value for a comfortable ride.

2train per day
20h 38mAverage Duration
$193Cheapest ticket
107kgCO₂ emissions

Bus Rochester, NY, US to St. Louis: Trip Overview

Average ticket price$155
Average bus trip duration1d 4h
Number of daily buses3
Earliest bus departure5:10am
Distance727 miles (1171 km)
Latest bus departure11:50pm

Rochester to St. Louis Bus

Busbud helps you find a bus from Rochester to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Rochester to St. Louis will be provided by the most trusted bus companies.

Discover how much the bus trip from Rochester to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Rochester, NY, US - St. Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/29
$147
07/30
$162
Today
$148
08/01
$148
08/02
No data
08/03
No data
08/04
No data
08/05
No data
busbud logoThe cheapest trip from Rochester, NY, US to St. Louis was searched and found on Jul 29, 2025 with a price of $147

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester, NY, US to St. Louis, as early as possible.

You can expect to pay from $147 to $201 for a bus ticket from Rochester, NY, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $148 which is on 2025-08-01.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Rochester and St. Louis!

Much more than a mere vehicle taking you from Rochester to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Rochester to St. Louis will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Rochester to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Rochester, NY, US to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Rochester, NY, US by bus?

Bus from Rochester, NY, US to St. Louis

You can also go to St. Louis by train

Train from Rochester, NY, US to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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