Bus Tickets from Palermo to Prague

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Previously seen trips

One passenger / one way

  • Departure time: August 24 at
    Departure city: Palermo
    Departure location: Terminal Bus Palermo
    Arrival time: August 26 at
    Destination city: Prague
    Destination location: PRG Airport
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 24 at
    Departure city: Palermo
    Departure location: Terminal Bus Palermo
    Arrival time: August 26 at
    Destination city: Prague
    Destination location: PRG Airport
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 24 at
    Departure city: Palermo
    Departure location: Terminal Bus Palermo
    Arrival time: August 26 at
    Destination city: Prague
    Destination location: PRG Airport
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 23 at
    Departure city: Palermo
    Departure location: Terminal Bus Palermo
    Arrival time: August 25 at
    Destination city: Prague
    Destination location: Prague Hradčanská
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 23 at
    Departure city: Palermo
    Departure location: Terminal Bus Palermo
    Arrival time: August 25 at
    Destination city: Prague
    Destination location: Tomíčkova
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Bus Palermo to Prague: Trip Overview

Average ticket price$323
Average bus trip duration1d 21h
Number of daily buses9
Earliest bus departure9:10am
Distance825 miles (1330 km)
Latest bus departure6:15pm

Palermo to Prague Bus

With Busbud, comparing and booking tickets for a bus from Palermo to Prague is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Palermo to Prague from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Prague from Palermo, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Palermo - Prague

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/20
No data
08/21
No data
Today
No data
08/23
$288
08/24
$235
08/25
No data
08/26
No data
08/27
No data
busbud logoThe cheapest trip from Palermo to Prague was searched and found on Aug 24, 2025 with a price of $235

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Prague, as early as possible.

You can expect to pay from $235 to $372 for a bus ticket from Palermo to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $235 which is on 2025-08-24.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Palermo to Prague.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Palermo to Prague, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Palermo to Prague.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Palermo to Prague.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Palermo by bus?

Bus from Prague to Palermo

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