Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal Bus Palermo | Lampugnano | Cheapest | |||||
| Terminal Bus Palermo | Milan San Donato Bus Station | Fastest | |||||
| Terminal Bus Palermo | Milan San Donato Bus Station | No tags | |||||
 | Terminal Bus Palermo | Milan (Malpensa Aeroporto Terminal 1) | No tags | |||||
| Terminal Bus Palermo | Aeroporto Malpensa T2 | No tags |
Accepted payments
Compare 2 ways to go from Palermo to Milano.
| Average Price | Average Duration | CO₂ emissions | |||
|---|---|---|---|---|---|
| Average Price$61 - $295 | Average Duration1d | 22kg CO₂e5 out of 5 stars | CheapestMost eco-friendly | ||
Carpool | Average Price$101 - $114 | Average Duration16h 20m | 37kg CO₂e4 out of 5 stars | Fastest |
Busbud recommends carpooling from Palermo to MilanoAmong the sustainable travel choices, the carpool stands out as the good way to reach Milano. The journey takes about 16 hours 20 minutes and with fares starting at just $101, it presents an excellent value for a comfortable ride.
Bus Palermo to Milano: Trip Overview
Compare bus companies
Palermo to Milano Bus
With Busbud, comparing and booking tickets for a bus from Palermo to Milano is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Palermo to Milano.
Discover how much the bus trip from Palermo to Milano will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Palermo and Milano?
Frequently asked questions for your trip Palermo - Milano
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Palermo to Milano was searched and found on Aug 30, 2025 with a price of $79To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Milano, as early as possible.
You can expect to pay from $79 to $295 for a bus ticket from Palermo to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $79 which is on 2025-08-30.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Palermo to Milano.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Palermo to Milano.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Palermo to Milano will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Palermo to Milano, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Top traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Buses Connecting Palermo
Buses Leaving from Palermo
- Bus from Palermo to Frosinone
- Bus Palermo - Porto
- Palermo - Modena
- Bus from Palermo to Maglie
- Bus Palermo - Amsterdam
- Palermo - Parma
- Bus from Palermo to Syracuse
- Bus Palermo - Marsala
- Palermo - Rome
- Bus from Palermo to Alcamo
- Bus Palermo - Terrasini
- Palermo - Mazara del Vallo
- Bus from Palermo to Castelvetrano
- Bus Palermo - Milano
- Palermo - Salemi
Buses Going to Palermo
- Bus from Cosenza to Palermo
- Bus Frosinone - Palermo
- Brescia - Palermo
- Bus from Bari to Palermo
- Bus Modena - Palermo
- Outlet - Palermo
- Bus from Syracuse to Palermo
- Bus Terrasini - Palermo
- Marsala - Palermo
- Bus from Rome to Palermo
- Bus Alcamo - Palermo
- Mazara del Vallo - Palermo
- Bus from Messina to Palermo
- Bus Gela - Palermo
- Naples - Palermo
Popular Buses Connecting Milano
Buses Leaving from Milano
- Bus from Milano to Sanremo
- Bus Milano - Zürich
- Milano - Bisceglie
- Bus from Milano to Monza
- Bus Milano - Bari
- Milano - Verona
- Bus from Milano to Como
- Bus Milano - Genoa
- Milano - Venice
- Bus from Milano to Florence
- Bus Milano - Breuil-Cervinia
- Milano - Courmayeur
- Bus from Milano to Naples
- Bus Milano - Padova
- Milano - Passo del Tonale
Buses Going to Milano
Popular routes in this country
- Bus from Bari to Matera
- Bus Catania - Syracuse
- Palermo - Trapani
- Bus from Milano to Bergamo
- Bus Venice - Cortina d'Ampezzo
- Bergamo - Milano
- Bus from Taormina to Catania
- Bus Naples - Rome
- Bologna - Florence
- Bus from Rome to Milano
- Bus Trapani - Palermo
- Florence - Rome
- Bus from Matera to Bari
- Bus Syracuse - Catania
- Rome - Venice